Feline FER antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-FER-Ag01	Recombinant Feline FER protein	3090
GMP-FEL-FER-Ab01	Anti-Feline FER mouse monoclonal antibody (mAb)	1953
GMP-FEL-FER-Ab02	Anti-Feline FER mouse monoclonal antibody (mAb)	1953
GMP-FEL-FER-Ab03	Anti-Feline FER human monoclonal antibody (mAb)	1953
GMP-FEL-FER-Ab04	Anti-Feline FER human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-FER-Ag01
Product Name	Recombinant Feline FER protein
Target/Biomarker	Feline Ferritin (FER)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Ferritin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FER level test of animal Cat/Feline with hemochromatosis.
Tag	His
Products description	Recombinant Feline FER protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-FER-Ab01, GMP-FEL-FER-Ab02
Product Name	Anti-Feline FER mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Ferritin (FER)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Ferritin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FER antibodies in FER level test of animal Cat/Feline with hemochromatosis.
Tag	mFc
Products description	Anti-Feline FER mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FER antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-FER-Ab03, GMP-FEL-FER-Ab04
Product Name	Anti-Feline FER human monoclonal antibody (mAb)
Target/Biomarker	Feline Ferritin (FER)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Ferritin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FER antibodies in FER level test of animal Cat/Feline with hemochromatosis.
Tag	hFc
Products description	Anti-Feline FER human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FER antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

FER, the Fer protein, is a versatile and indispensable biomarker within the realm of cats (felines). This non-receptor tyrosine kinase is ubiquitously expressed across various feline tissues and cell types, exemplifying its profound significance in both normal physiological processes and pathological conditions. Structurally, FER features distinctive domains, including an N-terminal FER tyrosine kinase domain and a C-terminal domain specialized in protein-protein interactions. This molecular architecture equips FER with the ability to phosphorylate target proteins, orchestrating intricate intracellular signaling pathways. FER's multifaceted nature positions it as a key orchestrator of cellular functions in felines. A defining role of FER in felines is its involvement in the regulation of cell growth and proliferation. This non-receptor tyrosine kinase serves as a pivotal checkpoint in the complex signaling networks governing cellular division. When FER activity is perturbed or dysregulated, it can trigger uncontrolled cell growth, a cardinal feature of cancer. This aspect of FER biology holds profound implications for veterinary oncology. By measuring FER levels and scrutinizing its activity in feline tumors, clinicians can glean invaluable insights into cancer behavior, anticipate patient responses to treatments, and tailor therapeutic approaches for improved outcomes. Furthermore, ongoing investigations into FER's role in specific feline cancers may uncover novel therapeutic targets, bolstering the field of veterinary oncology.

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