Feline CBS antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-CBS-Ag01	Recombinant Feline CBS protein	3090
GMP-FEL-CBS-Ab01	Anti-Feline CBS mouse monoclonal antibody (mAb)	1953
GMP-FEL-CBS-Ab02	Anti-Feline CBS mouse monoclonal antibody (mAb)	1953
GMP-FEL-CBS-Ab03	Anti-Feline CBS human monoclonal antibody (mAb)	1953
GMP-FEL-CBS-Ab04	Anti-Feline CBS human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-CBS-Ag01
Product Name	Recombinant Feline CBS protein
Target/Biomarker	Feline cystathionine-β-synthase ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline cystathionine-β-synthase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Feline CBS protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CBS-Ab01, GMP-FEL-CBS-Ab02
Product Name	Anti-Feline CBS mouse monoclonal antibody (mAb)
Target/Biomarker	Feline cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Feline CBS mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CBS-Ab03, GMP-FEL-CBS-Ab04
Product Name	Anti-Feline CBS human monoclonal antibody (mAb)
Target/Biomarker	Feline cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Feline CBS human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline C-reactive Protein (fCRP) is a central biomarker in the realm of feline health, intricately linked to the cat's immune response to inflammatory challenges. Structurally, it is a pentameric protein, comprising five identical subunits, each with a molecular mass of approximately 25 kDa. Its hepatic synthesis is instigated by pro-inflammatory cytokines, most notably interleukin-6 (IL-6). The hallmark of fCRP lies in its rapid responsiveness to inflammation. When a cat encounters infectious agents, injuries, or other triggers that induce inflammation, the liver promptly commences the production of fCRP. This results in a significant increase in its concentration within the bloodstream, making fCRP a sentinel biomarker capable of detecting even subtle deviations from the norm in a cat's health. Functionally, fCRP serves as an acute-phase reactant. It actively participates in the innate immune system's response to inflammatory challenges. By enhancing opsonization and facilitating phagocytosis, fCRP plays a pivotal role in the removal of invading pathogens and damaged tissue, thus aiding in the resolution of inflammation.

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