Feline CBL antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-CBL-Ag01	Recombinant Feline CBL protein	3090
GMP-FEL-CBL-Ab01	Anti-Feline CBL mouse monoclonal antibody (mAb)	1953
GMP-FEL-CBL-Ab02	Anti-Feline CBL mouse monoclonal antibody (mAb)	1953
GMP-FEL-CBL-Ab03	Anti-Feline CBL human monoclonal antibody (mAb)	1953
GMP-FEL-CBL-Ab04	Anti-Feline CBL human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-CBL-Ag01
Product Name	Recombinant Feline CBL protein
Target/Biomarker	Toxoplasma Gondii (T.gondii)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Toxoplasma Gondii antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in T.gondii level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Feline CBL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CBL-Ab01, GMP-FEL-CBL-Ab02
Product Name	Anti-Feline CBL mouse monoclonal antibody (mAb)
Target/Biomarker	Toxoplasma Gondii (T.gondii)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Toxoplasma Gondii antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-T.gondii antibodies in T.gondii level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Feline CBL mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-T.gondii antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CBL-Ab03, GMP-FEL-CBL-Ab04
Product Name	Anti-Feline CBL human monoclonal antibody (mAb)
Target/Biomarker	Toxoplasma Gondii (T.gondii)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Toxoplasma Gondii antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-T.gondii antibodies in T.gondii level test of animal Cat/Feline with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Feline CBL human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-T.gondii antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cobalamin, known colloquially as Vitamin B12 and represented by the biomarker CBL, is a remarkable biochemical cornerstone within the feline (cat) community. This water-soluble vitamin serves as an essential cog in numerous metabolic pathways that are fundamental to feline health and well-being. Structurally, Vitamin B12 features a complex molecular arrangement with a central cobalt atom. This cobalt atom is the linchpin of Vitamin B12's biological activity, crucial for its role as a coenzyme in enzymatic reactions vital to feline physiology. Vitamin B12 plays a pivotal role in the metabolic conversion of methylmalonyl-CoA to succinyl-CoA, catalyzed by methylmalonyl-CoA mutase. This conversion has far-reaching implications, as it contributes to the metabolism of amino acids and fatty acids. Additionally, Vitamin B12 participates in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methionine is a foundational amino acid, and its synthesis is indispensable for protein production and overall cellular function. Beyond its involvement in amino acid and fatty acid metabolism, Vitamin B12 is integral to DNA synthesis. Cats rely on Vitamin B12 for the production of thymidine, one of the four nucleotide building blocks of DNA. This role is foundational for growth, tissue repair, and overall feline development. Vitamin B12's significance extends to the production of myelin, the insulating sheath that envelops nerve fibers. Myelin ensures efficient transmission of nerve impulses, underpinning neurological function. Furthermore, Vitamin B12 plays a key role in heme synthesis, a vital component of hemoglobin within red blood cells. Hemoglobin's function in oxygen transport makes it central to feline vitality.

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