Feline CA199 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-CA199-Ag01	Recombinant Feline CA199 protein	3090
GMP-FEL-CA199-Ab01	Anti-Feline CA199 mouse monoclonal antibody (mAb)	1953
GMP-FEL-CA199-Ab02	Anti-Feline CA199 mouse monoclonal antibody (mAb)	1953
GMP-FEL-CA199-Ab03	Anti-Feline CA199 human monoclonal antibody (mAb)	1953
GMP-FEL-CA199-Ab04	Anti-Feline CA199 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-CA199-Ag01
Product Name	Recombinant Feline CA199 protein
Target/Biomarker	Feline Carbohydrate antigen 19-9 (IBV - Variant 4/91)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Carbohydrate antigen 19-9 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IBV - Variant 4/91 level test of animal Cat/Feline with pancreatic and biliary tract tumors.
Tag	His
Products description	Recombinant Feline CA199 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CA199-Ab01, GMP-FEL-CA199-Ab02
Product Name	Anti-Feline CA199 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Carbohydrate antigen 19-9 (IBV - Variant 4/91)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Carbohydrate antigen 19-9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 4/91 antibodies in IBV - Variant 4/91 level test of animal Cat/Feline with pancreatic and biliary tract tumors.
Tag	mFc
Products description	Anti-Feline CA199 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 4/91 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-CA199-Ab03, GMP-FEL-CA199-Ab04
Product Name	Anti-Feline CA199 human monoclonal antibody (mAb)
Target/Biomarker	Feline Carbohydrate antigen 19-9 (IBV - Variant 4/91)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Carbohydrate antigen 19-9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 4/91 antibodies in IBV - Variant 4/91 level test of animal Cat/Feline with pancreatic and biliary tract tumors.
Tag	hFc
Products description	Anti-Feline CA199 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 4/91 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cancer Antigen 199 (CA199) is a glycoprotein biomarker that assumes a pivotal role in feline health, particularly in the sphere of cancer diagnosis and monitoring. This biomarker is associated with several types of cancer in cats, including those affecting the pancreas, gastrointestinal tract, and liver. Structurally, CA199 is classified as a carbohydrate antigen, featuring a protein core with attached carbohydrate molecules. In the context of feline health, CA199 assumes significance as a diagnostic tool for the early detection of cancer. Cancers affecting the pancreas, gastrointestinal tract, or liver can be insidious, often presenting with subtle or nonspecific clinical signs. CA199 blood tests offer a non-invasive and sensitive means of identifying these malignancies, allowing for timely intervention and potentially improving treatment outcomes. CA199 levels in a cat's bloodstream become elevated when cancer cells, particularly those found in pancreatic, gastrointestinal, or hepatic cancers, produce and release this glycoprotein. As a result, CA199 serves as a biomarker that can be readily detected and quantified through blood tests.

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