Feline BNP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-BNP-Ag01	Recombinant Feline BNP protein	3090
GMP-FEL-BNP-Ab01	Anti-Feline BNP mouse monoclonal antibody (mAb)	1953
GMP-FEL-BNP-Ab02	Anti-Feline BNP mouse monoclonal antibody (mAb)	1953
GMP-FEL-BNP-Ab03	Anti-Feline BNP human monoclonal antibody (mAb)	1953
GMP-FEL-BNP-Ab04	Anti-Feline BNP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-BNP-Ag01
Product Name	Recombinant Feline BNP protein
Target/Biomarker	Feline B-type natriuretic peptide ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline B-type natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Cat/Feline with Cardiovascular Disease.
Tag	His
Products description	Recombinant Feline BNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-BNP-Ab01, GMP-FEL-BNP-Ab02
Product Name	Anti-Feline BNP mouse monoclonal antibody (mAb)
Target/Biomarker	Feline B-type natriuretic peptide ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline B-type natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with Cardiovascular Disease.
Tag	mFc
Products description	Anti-Feline BNP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-BNP-Ab03, GMP-FEL-BNP-Ab04
Product Name	Anti-Feline BNP human monoclonal antibody (mAb)
Target/Biomarker	Feline B-type natriuretic peptide ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline B-type natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with Cardiovascular Disease.
Tag	hFc
Products description	Anti-Feline BNP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline B-type Natriuretic Peptide, commonly referred to as Feline BNP, assumes a central role in the intricate web of feline cardiovascular health. Synthesized predominantly within the ventricles of the heart in domestic cats (Felis catus), this peptide hormone is a key player in the regulation of blood pressure and fluid balance. It is part of the larger natriuretic peptide family, with atrial natriuretic peptide (ANP) as its companion, orchestrating the physiological symphony of cardiovascular stability. The production and release of Feline BNP are finely tuned processes, responsive to the demands placed on the feline heart. When the heart encounters increased pressure or volume overload, often due to conditions like congestive heart failure (CHF), valvular disease, or cardiomyopathy, the ventricles react by liberating Feline BNP into the bloodstream. This response serves as a natural mechanism to alleviate the cardiac workload and maintain blood pressure within the ideal range. The actions of Feline BNP are executed through its binding to specific receptors in the kidneys and blood vessels. This binding event initiates a cascade of events leading to increased excretion of sodium and water by the kidneys, promoting diuresis. This diuretic effect translates into a reduction in blood volume, a lightened burden on the heart, and the restoration of cardiovascular equilibrium.

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