Feline β-CTx antibody and antigen (recombinant protein)

Diagnostic anti-Feline β-CTx antibodies pairs and antigen for animal health (animal Cat/Feline osteoporosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-FEL-B-CTx-Ag01 Recombinant Feline β-CTx protein 3090
GMP-FEL-B-CTx-Ab01 Anti-Feline β-CTx mouse monoclonal antibody (mAb) 1953
GMP-FEL-B-CTx-Ab02 Anti-Feline β-CTx mouse monoclonal antibody (mAb) 1953
GMP-FEL-B-CTx-Ab03 Anti-Feline β-CTx human monoclonal antibody (mAb) 1953
GMP-FEL-B-CTx-Ab04 Anti-Feline β-CTx human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-FEL-B-CTx-Ag01
Product Name Recombinant Feline β-CTx protein
Target/Biomarker Feline β-isomerized C-terminal telopeptides (β-CTx)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Feline β-isomerized C-terminal telopeptides antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in β-CTx level test of animal Cat/Feline with osteoporosis.
Tag His
Products description Recombinant Feline β-CTx protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-FEL-B-CTx-Ab01, GMP-FEL-B-CTx-Ab02
Product Name Anti-Feline β-CTx mouse monoclonal antibody (mAb)
Target/Biomarker Feline β-isomerized C-terminal telopeptides (β-CTx)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Feline β-isomerized C-terminal telopeptides antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-β-CTx antibodies in β-CTx level test of animal Cat/Feline with osteoporosis.
Tag mFc
Products description Anti-Feline β-CTx mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-β-CTx antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-FEL-B-CTx-Ab03, GMP-FEL-B-CTx-Ab04
Product Name Anti-Feline β-CTx human monoclonal antibody (mAb)
Target/Biomarker Feline β-isomerized C-terminal telopeptides (β-CTx)
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Feline β-isomerized C-terminal telopeptides antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-β-CTx antibodies in β-CTx level test of animal Cat/Feline with osteoporosis.
Tag hFc
Products description Anti-Feline β-CTx human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-β-CTx antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Feline β-CTx (Beta-CrossLaps) stands as a pivotal biomarker within the feline species, Felis catus. Its significance lies in its role as a marker of bone resorption, a fundamental process in bone metabolism. This biomarker is inexorably tied to the dynamic world of feline skeletal health. In the intricate dance of bone metabolism, β-CTx represents a beacon of bone resorption, a process wherein old or damaged bone tissue is methodically broken down. This process is orchestrated by specialized cells known as osteoclasts, which actively release fragments of type I collagen, including β-CTx, into the bloodstream. This biomarker, therefore, provides a quantifiable measure of the rate at which bone tissue is being resorbed in cats. The importance of Feline β-CTx extends beyond its role in bone resorption. It serves as a sentinel, continuously monitoring the balance between bone formation and resorption, a crucial equilibrium in maintaining skeletal health in cats. Alterations in this balance, often indicated by changes in β-CTx levels, can be early indicators of bone disorders or diseases.



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    GDU

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