Feline ANP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-ANP-Ag01	Recombinant Feline ANP protein	3090
GMP-FEL-ANP-Ab01	Anti-Feline ANP mouse monoclonal antibody (mAb)	1953
GMP-FEL-ANP-Ab02	Anti-Feline ANP mouse monoclonal antibody (mAb)	1953
GMP-FEL-ANP-Ab03	Anti-Feline ANP human monoclonal antibody (mAb)	1953
GMP-FEL-ANP-Ab04	Anti-Feline ANP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-ANP-Ag01
Product Name	Recombinant Feline ANP protein
Target/Biomarker	Mycoplasma Gallisepticum ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Mycoplasma Gallisepticum antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
Tag	His
Products description	Recombinant Feline ANP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-ANP-Ab01, GMP-FEL-ANP-Ab02
Product Name	Anti-Feline ANP mouse monoclonal antibody (mAb)
Target/Biomarker	Mycoplasma Gallisepticum ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Mycoplasma Gallisepticum antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
Tag	mFc
Products description	Anti-Feline ANP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-ANP-Ab03, GMP-FEL-ANP-Ab04
Product Name	Anti-Feline ANP human monoclonal antibody (mAb)
Target/Biomarker	Mycoplasma Gallisepticum ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Mycoplasma Gallisepticum antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with hypertension, cardiac hypertrophy and heart failure.
Tag	hFc
Products description	Anti-Feline ANP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline Atrial Natriuretic Peptide, or Feline ANP, stands as a remarkable component of the intricate cardiovascular system within domestic cats (Felis catus). Its origin lies in the atrial myocardium, specifically the atria, which are the heart's upper chambers responsible for receiving blood returning from the body and sending it to the ventricles for pumping into circulation. Structurally, Feline ANP is a peptide hormone composed of a chain of amino acids. Its synthesis and release are governed by the heart's sensitivity to changes in atrial pressure, primarily in response to the stretching of atrial walls. This mechanism comes into play during conditions that impose additional workload on the heart, such as increased blood volume or pressure within the atria. The role of Feline ANP within the feline body is truly remarkable. Its primary function is to maintain cardiovascular homeostasis by orchestrating a series of responses that help regulate blood pressure, fluid balance, and electrolyte levels. One of its most notable actions is the promotion of vasodilation, which leads to the relaxation of blood vessels. This process helps to alleviate the strain on the heart, reducing cardiac workload and ultimately contributing to enhanced cardiac function. Additionally, Feline ANP is a potent regulator of renal function. It enhances glomerular filtration rate (GFR) within the kidneys, which increases the rate at which blood is filtered to form urine. Moreover, Feline ANP inhibits sodium reabsorption in the renal tubules, facilitating increased sodium excretion in the urine. As sodium levels drop, water follows, aiding in the reduction of blood volume and blood pressure. These actions collectively contribute to the regulation of the body's fluid balance.

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