Feline AGP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-AGP-Ag01	Recombinant Feline AGP protein	3090
GMP-FEL-AGP-Ab01	Anti-Feline AGP mouse monoclonal antibody (mAb)	1953
GMP-FEL-AGP-Ab02	Anti-Feline AGP mouse monoclonal antibody (mAb)	1953
GMP-FEL-AGP-Ab03	Anti-Feline AGP human monoclonal antibody (mAb)	1953
GMP-FEL-AGP-Ab04	Anti-Feline AGP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-AGP-Ag01
Product Name	Recombinant Feline AGP protein
Target/Biomarker	Feline Alpha-1-acid glycoprotein (AGP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Alpha-1-acid glycoprotein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AGP level test of animal Cat/Feline with Systemic Inflammation.
Tag	His
Products description	Recombinant Feline AGP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-AGP-Ab01, GMP-FEL-AGP-Ab02
Product Name	Anti-Feline AGP mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Alpha-1-acid glycoprotein (AGP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Alpha-1-acid glycoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies in AGP level test of animal Cat/Feline with Systemic Inflammation.
Tag	mFc
Products description	Anti-Feline AGP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-AGP-Ab03, GMP-FEL-AGP-Ab04
Product Name	Anti-Feline AGP human monoclonal antibody (mAb)
Target/Biomarker	Feline Alpha-1-acid glycoprotein (AGP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Alpha-1-acid glycoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies in AGP level test of animal Cat/Feline with Systemic Inflammation.
Tag	hFc
Products description	Anti-Feline AGP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Alpha-1 Acid Glycoprotein (AGP), commonly referred to as Cat/Feline AGP when discussing its specific application within veterinary medicine for felines, is an acute phase protein that plays a pivotal role as a biomarker in detecting inflammation and various disease states in cats. This glycoprotein is synthesized predominantly in the liver and is released into the bloodstream in response to acute and chronic inflammation, infection, and trauma. Its concentration in the blood significantly increases as part of the body's innate immune response to stress, making it an invaluable indicator for veterinarians to assess the health and well-being of their feline patients. The measurement of AGP levels in cats provides a non-specific yet highly sensitive marker for inflammation. Unlike other biomarkers that might show fluctuations due to minor health changes or stress unrelated to disease, AGP levels elevate markedly only in response to significant physiological challenges. This characteristic makes AGP a reliable indicator for distinguishing between stress responses and underlying pathological conditions requiring medical intervention. In clinical practice, the utility of Cat/Feline AGP extends across a wide spectrum of applications. It is particularly beneficial in the early detection of diseases where clinical symptoms may not yet be evident. Diseases such as chronic kidney disease, inflammatory bowel disease, and various forms of cancer can subtly affect a cat's health before any overt signs become apparent. Monitoring AGP levels allows veterinarians to initiate diagnostic investigations and treatments earlier, potentially improving the prognosis and quality of life for affected cats. Furthermore, AGP levels are valuable in monitoring the progression or resolution of diseases. For instance, in cases of infectious diseases, such as feline infectious peritonitis (FIP), or in conditions requiring surgical intervention, periodic measurement of AGP can provide insights into the effectiveness of treatments or the healing process post-surgery. A decreasing trend in AGP levels often correlates with a positive response to treatment and recovery, while persistently high or increasing levels may indicate complications or the need for a reassessment of the treatment strategy. AGP's role in prognostication cannot be understated. Its levels can reflect the severity of a disease, aiding veterinarians in predicting outcomes and making informed decisions about treatment options. For example, higher AGP concentrations at diagnosis have been associated with more severe disease states and, in some cases, poorer prognoses. This information is crucial for veterinarians when discussing treatment plans and expectations with pet owners. The specificity of AGP as a biomarker for feline patients highlights the importance of species-specific research and diagnostic tools in veterinary medicine. Unlike human medicine, where a broad range of biomarkers has been studied extensively, the field of veterinary medicine requires targeted research to identify and validate biomarkers that are specific and relevant to different species. Cat/Feline AGP exemplifies the success of such endeavors, providing a tool that is finely tuned to the physiological responses of felines. In conclusion, Cat/Feline AGP is more than just a biomarker; it is a cornerstone of modern feline veterinary practice. Its ability to indicate the presence of inflammation and disease, even in the absence of clinical symptoms, empowers veterinarians to take proactive measures in managing feline health. As research continues to advance, the potential applications of AGP and other biomarkers will further enhance the ability of veterinary professionals to diagnose, treat, and manage the myriad of health challenges faced by cats.

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