Feline ACRV1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-ACRV1-Ag01	Recombinant Feline ACRV1 protein	3090
GMP-FEL-ACRV1-Ab01	Anti-Feline ACRV1 mouse monoclonal antibody (mAb)	1953
GMP-FEL-ACRV1-Ab02	Anti-Feline ACRV1 mouse monoclonal antibody (mAb)	1953
GMP-FEL-ACRV1-Ab03	Anti-Feline ACRV1 human monoclonal antibody (mAb)	1953
GMP-FEL-ACRV1-Ab04	Anti-Feline ACRV1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-ACRV1-Ag01
Product Name	Recombinant Feline ACRV1 protein
Target/Biomarker	Feline acrosome protein (ACRV1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline acrosome protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACRV1 level test of animal Cat/Feline with Fertilization.
Tag	His
Products description	Recombinant Feline ACRV1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-ACRV1-Ab01, GMP-FEL-ACRV1-Ab02
Product Name	Anti-Feline ACRV1 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline acrosome protein (ACRV1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline acrosome protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies in ACRV1 level test of animal Cat/Feline with Fertilization.
Tag	mFc
Products description	Anti-Feline ACRV1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-ACRV1-Ab03, GMP-FEL-ACRV1-Ab04
Product Name	Anti-Feline ACRV1 human monoclonal antibody (mAb)
Target/Biomarker	Feline acrosome protein (ACRV1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline acrosome protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies in ACRV1 level test of animal Cat/Feline with Fertilization.
Tag	hFc
Products description	Anti-Feline ACRV1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline ACRV1, or Acrosome Protein ACRV1, stands as a linchpin in the intricate machinery of feline reproduction. This protein, predominantly housed within the acrosome—a specialized organelle that caps the head of mature sperm—holds the key to one of life's most critical processes: fertilization. Structurally, ACRV1 is a glycoprotein integral to the acrosome's composition. The acrosome is a sac-like structure containing enzymes and proteins crucial for sperm-egg interaction and penetration. ACRV1's role commences at the moment of sperm-egg contact, where it engages in sperm-egg binding and membrane fusion. These initial steps set the stage for the subsequent acrosomal reaction. The acrosomal reaction, orchestrated in part by ACRV1, is a cascade of events that unfolds as the sperm approaches the egg. It entails the release of acrosomal enzymes that digest the zona pellucida, a glycoprotein-rich layer surrounding the egg. ACRV1 contributes to the breakdown of the zona pellucida, facilitating the penetration of the egg's protective layers. Furthermore, ACRV1's function extends beyond the confines of fertilization. It is believed to play a role in the formation and maintenance of the acrosome itself. A well-formed and intact acrosome is vital for sperm function, and disruptions in ACRV1 expression or function can affect the acrosome's structural integrity.

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