Equine sST2 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-sST2-Ag01	Recombinant Equine sST2 protein	3090
GMP-EQU-sST2-Ab01	Anti-Equine sST2 mouse monoclonal antibody (mAb)	1953
GMP-EQU-sST2-Ab02	Anti-Equine sST2 mouse monoclonal antibody (mAb)	1953
GMP-EQU-sST2-Ab03	Anti-Equine sST2 human monoclonal antibody (mAb)	1953
GMP-EQU-sST2-Ab04	Anti-Equine sST2 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-sST2-Ag01
Product Name	Recombinant Equine sST2 protein
Target/Biomarker	Equine soluble ST2 (sST2)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine soluble ST2 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sST2 level test of animal Equine/Horse with chronic and acute heart failure.
Tag	His
Products description	Recombinant Equine sST2 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-sST2-Ab01, GMP-EQU-sST2-Ab02
Product Name	Anti-Equine sST2 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine soluble ST2 (sST2)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine soluble ST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sST2 antibodies in sST2 level test of animal Equine/Horse with chronic and acute heart failure.
Tag	mFc
Products description	Anti-Equine sST2 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sST2 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-sST2-Ab03, GMP-EQU-sST2-Ab04
Product Name	Anti-Equine sST2 human monoclonal antibody (mAb)
Target/Biomarker	Equine soluble ST2 (sST2)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine soluble ST2 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sST2 antibodies in sST2 level test of animal Equine/Horse with chronic and acute heart failure.
Tag	hFc
Products description	Anti-Equine sST2 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sST2 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Soluble ST2 (sST2) in horses represents a multifaceted biomarker intricately intertwined with equine cardiovascular health. It assumes a critical role in immune responses, inflammation regulation, and cardiac function, playing a pivotal role in the complex interplay of cardiac stress, injury, and recovery. To delve deeper, sST2 serves as a receptor for interleukin-33 (IL-33), a cytokine with potent anti-inflammatory and protective effects, particularly within the cardiovascular system. In horses, sST2 primarily originates from cardiac cells, notably cardiomyocytes. Its soluble form, detectable in the bloodstream, functions as an essential biomarker for assessing cardiac health and identifying underlying cardiac pathologies. Elevated sST2 levels in horses are often a result of cardiac stress, injury, or inflammation. This makes sST2 a vital tool for diagnosing and monitoring a spectrum of cardiac conditions, ranging from myocarditis (inflammation of the heart muscle) to heart failure and beyond. The dynamic response of sST2 to cardiac strain positions it as a sensitive and precise marker for identifying equine patients at risk of cardiac disorders.

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