Equine relaxin antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-relaxin-Ag01	Recombinant Equine relaxin protein	3090
GMP-EQU-relaxin-Ab01	Anti-Equine relaxin mouse monoclonal antibody (mAb)	1953
GMP-EQU-relaxin-Ab02	Anti-Equine relaxin mouse monoclonal antibody (mAb)	1953
GMP-EQU-relaxin-Ab03	Anti-Equine relaxin human monoclonal antibody (mAb)	1953
GMP-EQU-relaxin-Ab04	Anti-Equine relaxin human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-relaxin-Ag01
Product Name	Recombinant Equine relaxin protein
Target/Biomarker	Equine relaxin (RLN)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine relaxin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in RLN level test of animal Equine/Horse with Pregnancy.
Tag	His
Products description	Recombinant Equine relaxin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-relaxin-Ab01, GMP-EQU-relaxin-Ab02
Product Name	Anti-Equine relaxin mouse monoclonal antibody (mAb)
Target/Biomarker	Equine relaxin (RLN)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine relaxin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-RLN antibodies in RLN level test of animal Equine/Horse with Pregnancy.
Tag	mFc
Products description	Anti-Equine relaxin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-RLN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-relaxin-Ab03, GMP-EQU-relaxin-Ab04
Product Name	Anti-Equine relaxin human monoclonal antibody (mAb)
Target/Biomarker	Equine relaxin (RLN)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine relaxin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-RLN antibodies in RLN level test of animal Equine/Horse with Pregnancy.
Tag	hFc
Products description	Anti-Equine relaxin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-RLN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Relaxin, a multifaceted peptide hormone, takes center stage in the intricate drama of reproductive physiology and tissue remodeling in mammals, including humans and dogs. This remarkable hormone, a member of the insulin/relaxin superfamily, stands as a testament to the intricate interplay of molecular signals governing pivotal life processes. Structurally, relaxin is characterized by its complex chain of amino acids, and its synthesis primarily occurs in the corpus luteum during pregnancy. This temporary endocrine gland within the ovaries emerges post-ovulation and serves as the primary source of relaxin production. In the context of pregnancy, relaxin orchestrates a symphony of physiological changes to ensure the successful progression of gestation. Among its primary roles is the promotion of uterine relaxation. By relaxing the smooth muscles of the uterus, relaxin prevents premature contractions, providing a safe environment for the developing fetus. This uterine relaxation also facilitates the dilation of the cervix during labor, allowing for the passage of the newborn. Beyond its impact on uterine and cervical physiology, relaxin extends its reach to the cardiovascular system. During pregnancy, it plays a crucial role in vasodilation, leading to the expansion of blood vessels. This adaptive response ensures increased blood flow to the uterus and placenta, facilitating the exchange of vital nutrients and oxygen between the mother and the developing embryo. It is this finely orchestrated vascular dance that supports the nourishment and growth of the fetus. Interestingly, relaxin's influence isn't confined to pregnancy alone. It also plays a role in tissue remodeling, affecting processes such as wound healing and collagen metabolism. In these contexts, relaxin promotes the breakdown of collagen, the principal structural protein in connective tissues. This effect can be particularly relevant in the management of conditions involving fibrosis or scar tissue formation.

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