Equine/Horse lactoferrin antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-lactoferrin-Ag01	Recombinant Equine/Horse lactoferrin protein	3090
GMP-EQU-lactoferrin-Ab01	Anti-Equine/Horse lactoferrin mouse monoclonal antibody (mAb)	1953
GMP-EQU-lactoferrin-Ab02	Anti-Equine/Horse lactoferrin mouse monoclonal antibody (mAb)	1953
GMP-EQU-lactoferrin-Ab03	Anti-Equine/Horse lactoferrin human monoclonal antibody (mAb)	1953
GMP-EQU-lactoferrin-Ab04	Anti-Equine/Horse lactoferrin human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-lactoferrin-Ag01
Product Name	Recombinant Equine/Horse lactoferrin protein
Target/Biomarker	Equine/Horse lactoferrin ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine/Horse lactoferrin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Equine/Horse with Intestinal Health.
Tag	His
Products description	Recombinant Equine/Horse lactoferrin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-lactoferrin-Ab01, GMP-EQU-lactoferrin-Ab02
Product Name	Anti-Equine/Horse lactoferrin mouse monoclonal antibody (mAb)
Target/Biomarker	Equine/Horse lactoferrin ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine/Horse lactoferrin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with Intestinal Health.
Tag	mFc
Products description	Anti-Equine/Horse lactoferrin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-lactoferrin-Ab03, GMP-EQU-lactoferrin-Ab04
Product Name	Anti-Equine/Horse lactoferrin human monoclonal antibody (mAb)
Target/Biomarker	Equine/Horse lactoferrin ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine/Horse lactoferrin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with Intestinal Health.
Tag	hFc
Products description	Anti-Equine/Horse lactoferrin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine lactoferrin is an essential glycoprotein in horses, embodying a suite of protective and regulatory functions similar to those observed in other mammals. As part of the transferrin family, it is recognized for its potent iron-binding capacity, playing a pivotal role in immune defense, inflammation modulation, and iron metabolism. This protein is present in various bodily fluids, including milk, saliva, and mucosal secretions, where it acts as a critical component of the innate immune system in horses. Antimicrobial Properties: Lactoferrin in horses exhibits broad-spectrum antimicrobial activity against a variety of pathogens, including bacteria, viruses, fungi, and parasites. Its ability to bind iron deprives these microorganisms of a vital growth factor, effectively inhibiting their proliferation. Additionally, lactoferrin can directly interact with the cell membranes of pathogens, disrupting their structure and function, which contributes to its protective role against infections in the equine population. Immune System Modulation: Beyond its antimicrobial functions, equine lactoferrin is instrumental in modulating the immune response. It enhances the activity of immune cells, such as neutrophils, macrophages, and lymphocytes, thereby strengthening the horse's immune defense mechanisms. Lactoferrin also possesses anti-inflammatory properties, helping to mitigate the effects of excessive inflammation and protect against tissue damage during immune responses. This is particularly valuable for managing conditions like respiratory diseases, which are common in horses and often have an inflammatory component. Support of Intestinal Health: Lactoferrin contributes to the maintenance of gut health in horses by promoting the growth of beneficial gut microbiota and improving the integrity of the gut barrier. This function is crucial for nutrient absorption, protection against enteric pathogens, and overall gastrointestinal health. For foals, the lactoferrin found in mare's colostrum is vital for establishing a healthy gut microbiome and supporting the development of the immune system early in life. Regulation of Iron Metabolism and Antioxidant Effects: Lactoferrin's role in iron metabolism involves regulating the availability of iron within the body, supporting essential biological processes while preventing excessive iron that could promote oxidative stress or microbial growth. Its antioxidant properties further protect cells from damage caused by free radicals, contributing to the overall health and well-being of horses. Therapeutic and Nutritional Applications: Given its beneficial properties, lactoferrin holds potential for therapeutic and nutritional applications in equine health care. Its inclusion in supplements can support immune function, promote gut health, and offer protective benefits against infections. Research into the specific applications of lactoferrin in equine medicine is ongoing, with the aim of harnessing its properties to enhance disease prevention, treatment strategies, and the nutritional management of horses. In summary, equine lactoferrin is a vital component of the horse's natural defense system, offering antimicrobial protection, immune modulation, and support for gut health, among other benefits. Its multifunctional nature and potential therapeutic applications highlight the importance of lactoferrin in promoting the health and performance of horses, underscoring the value of ongoing research and development in equine nutrition and health care.

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