Equine hemoglobin antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-hemoglobin-Ag01	Recombinant Equine hemoglobin protein	3090
GMP-EQU-hemoglobin-Ab01	Anti-Equine hemoglobin mouse monoclonal antibody (mAb)	1953
GMP-EQU-hemoglobin-Ab02	Anti-Equine hemoglobin mouse monoclonal antibody (mAb)	1953
GMP-EQU-hemoglobin-Ab03	Anti-Equine hemoglobin human monoclonal antibody (mAb)	1953
GMP-EQU-hemoglobin-Ab04	Anti-Equine hemoglobin human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-hemoglobin-Ag01
Product Name	Recombinant Equine hemoglobin protein
Target/Biomarker	Equine Hemoglobin (hemoglobin)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Hemoglobin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in hemoglobin level test of animal Equine/Horse with Anemia.
Tag	His
Products description	Recombinant Equine hemoglobin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-hemoglobin-Ab01, GMP-EQU-hemoglobin-Ab02
Product Name	Anti-Equine hemoglobin mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Hemoglobin (hemoglobin)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hemoglobin antibodies in hemoglobin level test of animal Equine/Horse with Anemia.
Tag	mFc
Products description	Anti-Equine hemoglobin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hemoglobin antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-hemoglobin-Ab03, GMP-EQU-hemoglobin-Ab04
Product Name	Anti-Equine hemoglobin human monoclonal antibody (mAb)
Target/Biomarker	Equine Hemoglobin (hemoglobin)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Hemoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hemoglobin antibodies in hemoglobin level test of animal Equine/Horse with Anemia.
Tag	hFc
Products description	Anti-Equine hemoglobin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hemoglobin antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Hemoglobin is a critical protein in horses, as in all vertebrates, that functions mainly within red blood cells to transport oxygen from the lungs to the body's tissues and to carry carbon dioxide from the tissues back to the lungs for exhalation. Here are some key aspects of equine hemoglobin: Oxygen Delivery: Hemoglobin enables horses to perform high levels of aerobic exercise by efficiently transporting oxygen. The hemoglobin in a horse's blood binds to oxygen in the lungs, and this oxygen-rich blood is then pumped by the heart to the muscles and other tissues that need it for energy production. Structure: Equine hemoglobin, like that of other mammals, is made up of four protein subunits, each containing an iron-bound heme group that can bind to one oxygen molecule. The structure is optimized for the reversible binding of oxygen, allowing it to be loaded and unloaded as needed. Hemoglobin Levels: The normal range of hemoglobin in horses varies slightly depending on the breed and individual, but it typically falls between 12 to 16 g/dL. These levels can be influenced by factors such as exercise, altitude, and health status. Anemia: If a horse has low hemoglobin levels, it is anemic. Anemia in horses can be caused by blood loss, hemolysis (destruction of red blood cells), iron deficiency, or diseases that suppress red blood cell production. Symptoms of anemia may include fatigue, weakness, and decreased performance, particularly in racehorses or sport horses. High Hemoglobin Levels: Elevated hemoglobin levels can occur due to dehydration, which results in a higher concentration of red blood cells relative to the volume of plasma. It can also be a response to chronic hypoxia, where the body adapts by producing more red blood cells to increase the oxygen-carrying capacity of the blood. Diagnostic and Monitoring Tool: Measuring hemoglobin is a routine part of a complete blood count (CBC) and is crucial for diagnosing various conditions in horses, from respiratory and metabolic diseases to performance issues. Veterinarians rely on hemoglobin levels to assess the animal's oxygen-carrying capacity and overall health status. Genetic Variations: Although less commonly discussed than in humans, horses can exhibit genetic variations in hemoglobin, which can affect oxygen affinity and transport efficiency. Research in this area can provide insights into breed-specific adaptations and performance characteristics. Nutrition: Adequate dietary iron and other nutrients are essential for the synthesis of hemoglobin. Nutritional deficiencies can lead to anemia, which is why proper equine nutrition is crucial for maintaining optimal hemoglobin levels. In conclusion, hemoglobin is indispensable in horses for maintaining physiological functions, particularly those related to oxygen transport and energy metabolism. Its levels are a critical indicator of equine health and performance, and monitoring these levels is a key component of veterinary care for horses.

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