Equine hEGF antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-hEGF-Ag01	Recombinant Equine hEGF protein	3090
GMP-EQU-hEGF-Ab01	Anti-Equine hEGF mouse monoclonal antibody (mAb)	1953
GMP-EQU-hEGF-Ab02	Anti-Equine hEGF mouse monoclonal antibody (mAb)	1953
GMP-EQU-hEGF-Ab03	Anti-Equine hEGF human monoclonal antibody (mAb)	1953
GMP-EQU-hEGF-Ab04	Anti-Equine hEGF human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-hEGF-Ag01
Product Name	Recombinant Equine hEGF protein
Target/Biomarker	Equine epidermal growth factor (hEGF)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine epidermal growth factor antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in hEGF level test of animal Equine/Horse with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	His
Products description	Recombinant Equine hEGF protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-hEGF-Ab01, GMP-EQU-hEGF-Ab02
Product Name	Anti-Equine hEGF mouse monoclonal antibody (mAb)
Target/Biomarker	Equine epidermal growth factor (hEGF)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine epidermal growth factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies in hEGF level test of animal Equine/Horse with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	mFc
Products description	Anti-Equine hEGF mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-hEGF-Ab03, GMP-EQU-hEGF-Ab04
Product Name	Anti-Equine hEGF human monoclonal antibody (mAb)
Target/Biomarker	Equine epidermal growth factor (hEGF)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine epidermal growth factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies in hEGF level test of animal Equine/Horse with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	hFc
Products description	Anti-Equine hEGF human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Human Epidermal Growth Factor (hEGF) is a protein with profound implications in cell biology and tissue regeneration. Although its origin is human, EGF-related molecules and signaling pathways have also been identified in horses (equines), albeit with structural differences. EGF is a member of the epidermal growth factor family, a group of proteins known for their pivotal roles in regulating cell growth, proliferation, and tissue repair. The principal receptor for EGF is the Epidermal Growth Factor Receptor (EGFR), which is present on the surface of various cell types. Upon binding to EGFR, EGF initiates a cascade of intracellular events that stimulate cell division, tissue repair, and the maintenance of healthy epithelial tissues. In horses, EGF-like molecules and their associated signaling pathways exhibit functional similarities to their human counterparts. While the specific structure of EGF in horses may not be identical to that in humans, the fundamental principles of EGF-mediated cellular responses are conserved. This implies that EGF pathways play essential roles in equine physiology, contributing to tissue homeostasis, repair, and regeneration.

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