Equine fFN antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-fFN-Ag01	Recombinant Equine fFN protein	3090
GMP-EQU-fFN-Ab01	Anti-Equine fFN mouse monoclonal antibody (mAb)	1953
GMP-EQU-fFN-Ab02	Anti-Equine fFN mouse monoclonal antibody (mAb)	1953
GMP-EQU-fFN-Ab03	Anti-Equine fFN human monoclonal antibody (mAb)	1953
GMP-EQU-fFN-Ab04	Anti-Equine fFN human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-fFN-Ag01
Product Name	Recombinant Equine fFN protein
Target/Biomarker	Equine Fetal fibronectin (fFN)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Fetal fibronectin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in fFN level test of animal Equine/Horse with premature delivery.
Tag	His
Products description	Recombinant Equine fFN protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-fFN-Ab01, GMP-EQU-fFN-Ab02
Product Name	Anti-Equine fFN mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Fetal fibronectin (fFN)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Fetal fibronectin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-fFN antibodies in fFN level test of animal Equine/Horse with premature delivery.
Tag	mFc
Products description	Anti-Equine fFN mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-fFN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-fFN-Ab03, GMP-EQU-fFN-Ab04
Product Name	Anti-Equine fFN human monoclonal antibody (mAb)
Target/Biomarker	Equine Fetal fibronectin (fFN)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Fetal fibronectin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-fFN antibodies in fFN level test of animal Equine/Horse with premature delivery.
Tag	hFc
Products description	Anti-Equine fFN human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-fFN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Fetal Fibronectin (e-fFN) stands as an indispensable sentinel in the realm of equine reproductive biology. This glycoprotein, uniquely situated within the amniotic fluid and placental tissues of pregnant horses, orchestrates the symphony of equine pregnancy. Structurally, e-fFN is part of the fibronectin family, a group of adhesive proteins renowned for their roles in cell adhesion and tissue organization. At its core, e-fFN serves as a molecular adhesive. During pregnancy, it acts as the adhesive that firmly binds developing equine fetuses to the uterine wall. This adhesion is not merely structural; it is the linchpin that ensures the stability of the maternal-fetal connection. Without the steadfast grip provided by e-fFN, developing foals could be at risk of detachment from the uterine lining, potentially leading to a cascade of complications. Beyond its adhesive prowess, e-fFN takes on an additional role in immune regulation. Pregnancy in horses presents a unique challenge for the maternal immune system. It must tolerate the presence of semi-allogeneic fetuses—offspring that share some, but not all, genetic material with the mother. e-fFN actively contributes to immune tolerance, ensuring that the mare's immune system does not launch a hostile response against the developing foal. This immunomodulatory function is pivotal for the success of equine pregnancies.

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