Equine cTnI antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-cTnI-Ag01	Recombinant Equine cTnI protein	3090
GMP-EQU-cTnI-Ab01	Anti-Equine cTnI mouse monoclonal antibody (mAb)	3090
GMP-EQU-cTnI-Ab02	Anti-Equine cTnI mouse monoclonal antibody (mAb)	3090
GMP-EQU-cTnI-Ab03	Anti-Equine cTnI human monoclonal antibody (mAb)	3090
GMP-EQU-cTnI-Ab04	Anti-Equine cTnI human monoclonal antibody (mAb)	3090

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-cTnI-Ag01
Product Name	Recombinant Equine cTnI protein
Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Alias of Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Cardiac Troponin I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
Tag	His
Products description	Recombinant Equine cTnI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-cTnI-Ab01, GMP-EQU-cTnI-Ab02
Product Name	Anti-Equine cTnI mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Alias of Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Cardiac Troponin I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies in cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
Tag	mFc
Products description	Anti-Equine cTnI mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-cTnI-Ab03, GMP-EQU-cTnI-Ab04
Product Name	Anti-Equine cTnI human monoclonal antibody (mAb)
Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Alias of Target/Biomarker	Equine Cardiac Troponin I (cTnI)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Cardiac Troponin I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies in cTnI level test of animal Equine/Horse with Myocardial injury, heart disease.
Tag	hFc
Products description	Anti-Equine cTnI human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cardiac Troponin I (cTnI) is a protein of exceptional significance in the context of equine physiology. This cardiac-specific biomarker is predominantly found in the bloodstream of horses (equines) and serves as a crucial indicator of cardiac health. To truly appreciate the role of cTnI, it is essential to delve into its structural composition, functional significance, and its position within the realm of equine cardiology. Structurally, cTnI is one of the three subunits of the troponin complex, the other two being cardiac Troponin T (cTnT) and cardiac Troponin C (cTnC). The troponin complex resides within the sarcomeres of cardiac muscle fibers, where it meticulously regulates muscle contraction. This precision is vital for the rhythmic and efficient pumping of blood by the horse's heart. What distinguishes cTnI is its exclusive cardiac specificity. While other troponin isoforms exist in skeletal muscle, cTnI is uniquely expressed in the heart. This specificity makes cTnI an exceptionally valuable biomarker for assessing cardiac muscle injury or damage. When cardiac cells are compromised due to factors such as myocardial infarction, cardiac diseases, or cardiac trauma, cTnI is released into the bloodstream. Therefore, elevated levels of cTnI in a horse's blood can serve as a critical diagnostic indicator of cardiac health. Detecting cTnI levels in equine serum is typically achieved through immunoassays, such as enzyme-linked immunosorbent assays (ELISA). These assays provide a quantitative measure of cTnI concentration, enabling veterinarians to assess the extent of cardiac injury or disease. The sensitivity of these assays is such that even minor myocardial damage can lead to detectable elevations in cTnI levels, allowing for early diagnosis and intervention.

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