Equine cIV antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-cIV-Ag01	Recombinant Equine cIV protein	3090
GMP-EQU-cIV-Ab01	Anti-Equine cIV mouse monoclonal antibody (mAb)	1953
GMP-EQU-cIV-Ab02	Anti-Equine cIV mouse monoclonal antibody (mAb)	1953
GMP-EQU-cIV-Ab03	Anti-Equine cIV human monoclonal antibody (mAb)	1953
GMP-EQU-cIV-Ab04	Anti-Equine cIV human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-cIV-Ag01
Product Name	Recombinant Equine cIV protein
Target/Biomarker	Feline Alpha-1-Microglobulin (A1M)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Alpha-1-Microglobulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of animal Equine/Horse with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag	His
Products description	Recombinant Equine cIV protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-cIV-Ab01, GMP-EQU-cIV-Ab02
Product Name	Anti-Equine cIV mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Alpha-1-Microglobulin (A1M)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Alpha-1-Microglobulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies in A1M level test of animal Equine/Horse with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag	mFc
Products description	Anti-Equine cIV mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-cIV-Ab03, GMP-EQU-cIV-Ab04
Product Name	Anti-Equine cIV human monoclonal antibody (mAb)
Target/Biomarker	Feline Alpha-1-Microglobulin (A1M)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Alpha-1-Microglobulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies in A1M level test of animal Equine/Horse with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag	hFc
Products description	Anti-Equine cIV human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Collagen Type IV (cIV) emerges as a silent sentinel within the expansive tapestry of equine biology, a master of structural integrity that quietly fortifies the extracellular matrix. As a member of the collagen family, cIV boasts a triple helical structure composed of three distinct polypeptide chains—a configuration that marries strength with flexibility, ideal for its role as the cornerstone of basement membranes. Basement membranes are far from passive foundations; they are bustling centers of cellular orchestration. cIV, at their core, offers not just architectural support but active participation in molecular signaling. Within basement membranes, cIV engages in intricate interplay with an ensemble of proteins and signaling molecules. This intricate web shapes a landscape where cellular adhesion, migration, growth, and differentiation are finely choreographed. Imagine cIV as the conductor of a symphony, ensuring harmonious cellular interactions, safeguarding structural stability, and orchestrating a molecular ballet that regulates vital physiological processes. Its role extends beyond the mechanical; it bridges the physical and molecular worlds, an architect and a communicator.

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