Equine α-defensin 5 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-a-defensin-5-Ag01	Recombinant Equine α-defensin 5 protein	3090
GMP-EQU-a-defensin-5-Ab01	Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb)	1953
GMP-EQU-a-defensin-5-Ab02	Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb)	1953
GMP-EQU-a-defensin-5-Ab03	Anti-Equine α-defensin 5 human monoclonal antibody (mAb)	1953
GMP-EQU-a-defensin-5-Ab04	Anti-Equine α-defensin 5 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-a-defensin-5-Ag01
Product Name	Recombinant Equine α-defensin 5 protein
Target/Biomarker	Equine alpha defensin 5 (α-defensin 5)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine alpha defensin 5 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI).
Tag	His
Products description	Recombinant Equine α-defensin 5 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-a-defensin-5-Ab01, GMP-EQU-a-defensin-5-Ab02
Product Name	Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine alpha defensin 5 (α-defensin 5)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine alpha defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-α-defensin 5 antibodies in α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI).
Tag	mFc
Products description	Anti-Equine α-defensin 5 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-α-defensin 5 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-a-defensin-5-Ab03, GMP-EQU-a-defensin-5-Ab04
Product Name	Anti-Equine α-defensin 5 human monoclonal antibody (mAb)
Target/Biomarker	Equine alpha defensin 5 (α-defensin 5)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine alpha defensin 5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-α-defensin 5 antibodies in α-defensin 5 level test of animal Equine/Horse with Prosthetic joint infection (PJI).
Tag	hFc
Products description	Anti-Equine α-defensin 5 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-α-defensin 5 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

α-defensin 5, commonly referred to as Def5, is a remarkable antimicrobial peptide residing within the equine (horse) digestive system. It belongs to the α-defensin family, a group of small cationic peptides renowned for their potent antimicrobial properties. In horses, α-defensin 5 plays a pivotal role in the innate immune system, primarily within the gastrointestinal tract. The production and secretion of α-defensin 5 primarily occur within specialized cells called Paneth cells. These cells are strategically located in the crypts of Lieberkühn in the small intestine, where they contribute significantly to maintaining intestinal health and defending against potential microbial threats. Structurally, α-defensin 5 boasts a unique configuration of cysteine residues that form disulfide bonds. These bonds not only confer structural stability but also enhance its antimicrobial activity. The primary function of α-defensin 5 is to target and neutralize a wide spectrum of pathogens, including bacteria, viruses, and fungi. By disrupting the integrity of microbial cell membranes, α-defensin 5 plays a pivotal role in the body's defense against invasive microorganisms.

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