Equine TrxR antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-TrxR-Ag01	Recombinant Equine TrxR protein	3090
GMP-EQU-TrxR-Ab01	Anti-Equine TrxR mouse monoclonal antibody (mAb)	1953
GMP-EQU-TrxR-Ab02	Anti-Equine TrxR mouse monoclonal antibody (mAb)	1953
GMP-EQU-TrxR-Ab03	Anti-Equine TrxR human monoclonal antibody (mAb)	1953
GMP-EQU-TrxR-Ab04	Anti-Equine TrxR human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-TrxR-Ag01
Product Name	Recombinant Equine TrxR protein
Target/Biomarker	Equine thioredoxin reductase (SAA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine thioredoxin reductase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAA level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	His
Products description	Recombinant Equine TrxR protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TrxR-Ab01, GMP-EQU-TrxR-Ab02
Product Name	Anti-Equine TrxR mouse monoclonal antibody (mAb)
Target/Biomarker	Equine thioredoxin reductase (SAA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	mFc
Products description	Anti-Equine TrxR mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TrxR-Ab03, GMP-EQU-TrxR-Ab04
Product Name	Anti-Equine TrxR human monoclonal antibody (mAb)
Target/Biomarker	Equine thioredoxin reductase (SAA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Equine/Horse with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	hFc
Products description	Anti-Equine TrxR human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Thioredoxin Reductase (TrxR) stands as a testament to the intricate biochemical machinery that safeguards the health of horses at the molecular level. This selenoprotein, distinguished by its dependence on the trace element selenium, plays a pivotal role within equine cells. Structurally, Equine TrxR comprises a fascinating blend of amino acids and selenium, arranged meticulously to form an enzyme of paramount importance. Its active site, housing the selenium atom, acts as the catalytic center for the reduction of thioredoxin, a fundamental player in the cellular antioxidant defense system. The primary function of Equine TrxR is to act as a vigilant guardian against the perils of oxidative stress. As horses go about their daily activities, their cells generate reactive oxygen species (ROS) as natural byproducts of metabolism. These ROS, if left unchecked, can wreak havoc within cells, causing damage to vital molecules such as proteins, lipids, and DNA. Equine TrxR steps in as the protector, diligently reducing the oxidized form of thioredoxin back to its active, reduced state. This restoration ensures that thioredoxin remains fully operational in its role of neutralizing ROS and maintaining the redox balance.

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