Equine TSH antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-TSH-Ag01	Recombinant Equine TSH protein	3090
GMP-EQU-TSH-Ab01	Anti-Equine TSH mouse monoclonal antibody (mAb)	1953
GMP-EQU-TSH-Ab02	Anti-Equine TSH mouse monoclonal antibody (mAb)	1953
GMP-EQU-TSH-Ab03	Anti-Equine TSH human monoclonal antibody (mAb)	1953
GMP-EQU-TSH-Ab04	Anti-Equine TSH human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-TSH-Ag01
Product Name	Recombinant Equine TSH protein
Target/Biomarker	Equine Thyroid Stimulating Hormone (sFlt-1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Thyroid Stimulating Hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of animal Equine/Horse with Hypothyroidism, hyperthyroidism.
Tag	His
Products description	Recombinant Equine TSH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TSH-Ab01, GMP-EQU-TSH-Ab02
Product Name	Anti-Equine TSH mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Thyroid Stimulating Hormone (sFlt-1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Thyroid Stimulating Hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies in sFlt-1 level test of animal Equine/Horse with Hypothyroidism, hyperthyroidism.
Tag	mFc
Products description	Anti-Equine TSH mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TSH-Ab03, GMP-EQU-TSH-Ab04
Product Name	Anti-Equine TSH human monoclonal antibody (mAb)
Target/Biomarker	Equine Thyroid Stimulating Hormone (sFlt-1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Thyroid Stimulating Hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies in sFlt-1 level test of animal Equine/Horse with Hypothyroidism, hyperthyroidism.
Tag	hFc
Products description	Anti-Equine TSH human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Thyroid-Stimulating Hormone (TSH) stands as a linchpin in the intricate web of hormonal regulation within the horse's body. This glycoprotein hormone, synthesized and secreted by the anterior pituitary gland, is an indispensable player in orchestrating thyroid function. Its primary role lies in stimulating the thyroid gland to produce and release thyroxine (T4) and triiodothyronine (T3), the two vital thyroid hormones that govern numerous physiological processes in horses. The production of TSH is triggered by thyrotropin-releasing hormone (TRH), released from the hypothalamus. Upon release into the bloodstream, TSH seeks out and binds to specific receptors on the surface of thyroid follicular cells. This binding event serves as a catalyst for the synthesis and release of T4 and T3. These thyroid hormones, in turn, regulate the horse's metabolic rate, energy production, and overall health. In essence, TSH serves as a sentinel, continually monitoring the horse's thyroid status and fine-tuning thyroid hormone production to maintain metabolic equilibrium. The delicate balance maintained by TSH ensures that the horse's energy needs are met, irrespective of their activity level, be it a performance horse or a leisurely pasture dweller.

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