Equine TPO antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-TPO-Ag01	Recombinant Equine TPO protein	3090
GMP-EQU-TPO-Ab01	Anti-Equine TPO mouse monoclonal antibody (mAb)	1953
GMP-EQU-TPO-Ab02	Anti-Equine TPO mouse monoclonal antibody (mAb)	1953
GMP-EQU-TPO-Ab03	Anti-Equine TPO human monoclonal antibody (mAb)	1953
GMP-EQU-TPO-Ab04	Anti-Equine TPO human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-TPO-Ag01
Product Name	Recombinant Equine TPO protein
Target/Biomarker	Equine Thyroid peroxidase (SCC Ag)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Thyroid peroxidase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SCC Ag level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
Tag	His
Products description	Recombinant Equine TPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TPO-Ab01, GMP-EQU-TPO-Ab02
Product Name	Anti-Equine TPO mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Thyroid peroxidase (SCC Ag)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Thyroid peroxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies in SCC Ag level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
Tag	mFc
Products description	Anti-Equine TPO mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TPO-Ab03, GMP-EQU-TPO-Ab04
Product Name	Anti-Equine TPO human monoclonal antibody (mAb)
Target/Biomarker	Equine Thyroid peroxidase (SCC Ag)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Thyroid peroxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies in SCC Ag level test of animal Equine/Horse with Hashimoto's disease or Graves' disease.
Tag	hFc
Products description	Anti-Equine TPO human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Thyroid Peroxidase (TPO) in horses (equines) stands as an unassuming yet pivotal biomarker, weaving the intricate tapestry of thyroid health, metabolic equilibrium, and overall vitality. Nestled predominantly within the thyroid gland, TPO conducts a symphony of enzymatic reactions critical to the synthesis of thyroid hormones. The defining function of TPO revolves around its catalytic prowess, culminating in the iodination of tyrosine residues on thyroglobulin. Thyroglobulin, a substantial glycoprotein manufactured within thyroid follicular cells, serves as the raw material for thyroid hormone production. TPO's intervention initiates the formation of thyroxine (T4) and triiodothyronine (T3), two thyroid hormones that wield profound regulatory authority over metabolic pathways, energy utilization, thermoregulation, growth, and various physiological systems in horses. TPO's catalytic mastery unfurls through a complex dance of iodination, wherein iodine atoms are judiciously incorporated onto specific tyrosine residues within thyroglobulin. This transformative process yields iodinated tyrosines, and subsequent coupling reactions between these iodinated tyrosines give rise to the biologically active thyroid hormones T4 and T3. These hormones represent the molecular maestros that govern the metabolic harmony of a horse's body.

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