Equine TNFα antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-TNFa-Ag01	Recombinant Equine TNFα protein	3090
GMP-EQU-TNFa-Ab01	Anti-Equine TNFα mouse monoclonal antibody (mAb)	1953
GMP-EQU-TNFa-Ab02	Anti-Equine TNFα mouse monoclonal antibody (mAb)	1953
GMP-EQU-TNFa-Ab03	Anti-Equine TNFα human monoclonal antibody (mAb)	1953
GMP-EQU-TNFa-Ab04	Anti-Equine TNFα human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-TNFa-Ag01
Product Name	Recombinant Equine TNFα protein
Target/Biomarker	Equine tumor necrosis factor alpha (SAHH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine tumor necrosis factor alpha antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of animal Equine/Horse with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	His
Products description	Recombinant Equine TNFα protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TNFa-Ab01, GMP-EQU-TNFa-Ab02
Product Name	Anti-Equine TNFα mouse monoclonal antibody (mAb)
Target/Biomarker	Equine tumor necrosis factor alpha (SAHH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine tumor necrosis factor alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Equine/Horse with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	mFc
Products description	Anti-Equine TNFα mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-TNFa-Ab03, GMP-EQU-TNFa-Ab04
Product Name	Anti-Equine TNFα human monoclonal antibody (mAb)
Target/Biomarker	Equine tumor necrosis factor alpha (SAHH)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine tumor necrosis factor alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Equine/Horse with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	hFc
Products description	Anti-Equine TNFα human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Tumor Necrosis Factor-alpha (TNFα), in the context of equines (horses), emerges as a multifaceted cytokine with a central role in orchestrating immune responses, inflammation, and tissue homeostasis. This pivotal biomarker belongs to the tumor necrosis factor superfamily, representing a critical arm of the equine immune system's defense mechanisms. Structurally, TNFα exists as a homotrimeric protein, and its functions span a spectrum of immune and inflammatory actions. It acts as a potent signaling molecule, binding to specific cell surface receptors, and initiating cascades of cellular responses. Its production is primarily attributed to immune cells within the horse's body, with macrophages and T cells being prominent sources.

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