Equine S100-A9 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-S100-A9-Ag01	Recombinant Equine S100-A9 protein	3090
GMP-EQU-S100-A9-Ab01	Anti-Equine S100-A9 mouse monoclonal antibody (mAb)	1953
GMP-EQU-S100-A9-Ab02	Anti-Equine S100-A9 mouse monoclonal antibody (mAb)	1953
GMP-EQU-S100-A9-Ab03	Anti-Equine S100-A9 human monoclonal antibody (mAb)	1953
GMP-EQU-S100-A9-Ab04	Anti-Equine S100-A9 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-S100-A9-Ag01
Product Name	Recombinant Equine S100-A9 protein
Target/Biomarker	Equine Calprotectin heavy chain (S100-A9)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Calprotectin heavy chain antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
Tag	His
Products description	Recombinant Equine S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-S100-A9-Ab01, GMP-EQU-S100-A9-Ab02
Product Name	Anti-Equine S100-A9 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Calprotectin heavy chain (S100-A9)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Calprotectin heavy chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
Tag	mFc
Products description	Anti-Equine S100-A9 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-S100-A9-Ab03, GMP-EQU-S100-A9-Ab04
Product Name	Anti-Equine S100-A9 human monoclonal antibody (mAb)
Target/Biomarker	Equine Calprotectin heavy chain (S100-A9)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Calprotectin heavy chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Equine/Horse with inflammatory bowel disease.
Tag	hFc
Products description	Anti-Equine S100-A9 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

S100-A9 in horses (equines) emerges as a pivotal biomarker with multifaceted roles that transcend its status as a mere indicator. It plays a central role in equine health, inflammation, and immunity, with a diverse range of functions that underscore its significance in equine physiology. S100-A9, also known as calgranulin B, belongs to the S100 protein family, a group of calcium-binding proteins celebrated for their involvement in various cellular processes, particularly those related to inflammation and immune responses. In horses, S100-A9 takes center stage in the innate immune system, predominantly produced by neutrophils and monocytes. The hallmark of S100-A9's functionality lies in its ability to form a heterodimeric complex with S100-A8, collectively referred to as S100A8/A9 or calprotectin. This complex is released by activated neutrophils and monocytes in response to inflammatory cues, thus serving as a sentinel of the innate immune response. Upon release into the extracellular environment, S100A8/A9 exerts potent pro-inflammatory effects, orchestrating the recruitment of immune cells to sites of infection or injury. Beyond its role as an inflammatory mediator, S100-A9 is implicated in a multitude of cellular processes within the equine body. It contributes to cell adhesion, facilitating interactions between immune cells and the endothelium lining blood vessels. Moreover, it plays a role in cell differentiation and tissue repair, underscoring its multifunctional nature. Of significant note is S100-A9's function as a damage-associated molecular pattern (DAMP) molecule. It acts as a sentinel, alerting the immune system to tissue damage or infection, thus enabling a rapid immune response. This feature highlights its significance in equine physiology, where it serves as a versatile player in immune regulation and tissue homeostasis.

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