Equine S100-A8 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-S100-A8-Ag01	Recombinant Equine S100-A8 protein	3090
GMP-EQU-S100-A8-Ab01	Anti-Equine S100-A8 mouse monoclonal antibody (mAb)	1953
GMP-EQU-S100-A8-Ab02	Anti-Equine S100-A8 mouse monoclonal antibody (mAb)	1953
GMP-EQU-S100-A8-Ab03	Anti-Equine S100-A8 human monoclonal antibody (mAb)	1953
GMP-EQU-S100-A8-Ab04	Anti-Equine S100-A8 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-S100-A8-Ag01
Product Name	Recombinant Equine S100-A8 protein
Target/Biomarker	Equine Calprotectin (S100-A8)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Calprotectin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A8 level test of animal Equine/Horse with intestinal inflammation.
Tag	His
Products description	Recombinant Equine S100-A8 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-S100-A8-Ab01, GMP-EQU-S100-A8-Ab02
Product Name	Anti-Equine S100-A8 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Calprotectin (S100-A8)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Calprotectin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A8 antibodies in S100-A8 level test of animal Equine/Horse with intestinal inflammation.
Tag	mFc
Products description	Anti-Equine S100-A8 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A8 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-S100-A8-Ab03, GMP-EQU-S100-A8-Ab04
Product Name	Anti-Equine S100-A8 human monoclonal antibody (mAb)
Target/Biomarker	Equine Calprotectin (S100-A8)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Calprotectin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A8 antibodies in S100-A8 level test of animal Equine/Horse with intestinal inflammation.
Tag	hFc
Products description	Anti-Equine S100-A8 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A8 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine S100-A8, a multifaceted calcium-binding protein, takes center stage in the intricate world of equine biology. Structurally, it forms a heterodimer with its counterpart, S100-A9, to create the calprotectin complex. In horses, this dynamic duo operates primarily within the confines of immune cells, particularly neutrophils and monocytes, where it plays a pivotal role in orchestrating the immune response. The hallmark of Equine S100-A8 is its rapid response to inflammatory cues. When the equine body detects a threat, whether it be a bacterial invader or tissue damage, immune cells spring into action. Equine S100-A8 is released from these activated cells into the bloodstream, where it embarks on its mission as a sentinel of inflammation. It serves as a signaling molecule, communicating with specific receptors like Toll-like receptor 4 (TLR4). This interaction triggers a cascade of events, leading to the recruitment of more immune cells to the site of injury or infection. Beyond its role in inflammation, Equine S100-A8 has a hand in tissue repair. It influences the migration and adhesion of neutrophils, helping to resolve inflammation and promote the healing of injured tissues. This dual nature of Equine S100-A8, as both a herald of inflammation and a facilitator of tissue recovery, underscores its significance in equine health.

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