Equine Proinsulin antibody and antigen (recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-Proinsulin-Ag01	Recombinant Equine Proinsulin protein	3090
GMP-EQU-Proinsulin-Ab01	Anti-Equine Proinsulin mouse monoclonal antibody (mAb)	3090
GMP-EQU-Proinsulin-Ab02	Anti-Equine Proinsulin mouse monoclonal antibody (mAb)	3090
GMP-EQU-Proinsulin-Ab03	Anti-Equine Proinsulin human monoclonal antibody (mAb)	3090
GMP-EQU-Proinsulin-Ab04	Anti-Equine Proinsulin human monoclonal antibody (mAb)	3090

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-Proinsulin-Ag01
Product Name	Recombinant Equine Proinsulin protein
Target/Biomarker	Equine Proinsulin ()
Alias of Target/Biomarker	Equine Proinsulin
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Equine/Horse with type 2 diabetes.
Tag	His
Products description	Recombinant Equine Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-Proinsulin-Ab01, GMP-EQU-Proinsulin-Ab02
Product Name	Anti-Equine Proinsulin mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Proinsulin ()
Alias of Target/Biomarker	Equine Proinsulin
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with type 2 diabetes.
Tag	mFc
Products description	Anti-Equine Proinsulin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-Proinsulin-Ab03, GMP-EQU-Proinsulin-Ab04
Product Name	Anti-Equine Proinsulin human monoclonal antibody (mAb)
Target/Biomarker	Equine Proinsulin ()
Alias of Target/Biomarker	Equine Proinsulin
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with type 2 diabetes.
Tag	hFc
Products description	Anti-Equine Proinsulin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Equine Proinsulin, an intricate 86-amino acid peptide hormone, holds a pivotal position in the intricate web of insulin biosynthesis within horses. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initial steps in insulin biosynthesis. The journey of Horse Proinsulin commences with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide is a distinguishing feature of proinsulin and plays a significant role in insulin biosynthesis. During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it regulates glucose metabolism by facilitating glucose uptake into cells. The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. Research suggests that the C-peptide may possess independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.

About GDU