Equine Proinsulin antibody and antigen (recombinant protein)

Diagnostic anti-Equine Proinsulin antibodies pairs and antigen for animal health (animal Equine/Horse type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Neurodegenerative diseases diagnostics products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-EQU-Proinsulin-Ag01 Recombinant Equine Proinsulin protein 3090
GMP-EQU-Proinsulin-Ab01 Anti-Equine Proinsulin mouse monoclonal antibody (mAb) 3090
GMP-EQU-Proinsulin-Ab02 Anti-Equine Proinsulin mouse monoclonal antibody (mAb) 3090
GMP-EQU-Proinsulin-Ab03 Anti-Equine Proinsulin human monoclonal antibody (mAb) 3090
GMP-EQU-Proinsulin-Ab04 Anti-Equine Proinsulin human monoclonal antibody (mAb) 3090

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-EQU-Proinsulin-Ag01
Product Name Recombinant Equine Proinsulin protein
Target/Biomarker Equine Proinsulin ()
Alias of Target/Biomarker Equine Proinsulin
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Equine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Equine/Horse with type 2 diabetes.
Tag His
Products description Recombinant Equine Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-EQU-Proinsulin-Ab01, GMP-EQU-Proinsulin-Ab02
Product Name Anti-Equine Proinsulin mouse monoclonal antibody (mAb)
Target/Biomarker Equine Proinsulin ()
Alias of Target/Biomarker Equine Proinsulin
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with type 2 diabetes.
Tag mFc
Products description Anti-Equine Proinsulin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-EQU-Proinsulin-Ab03, GMP-EQU-Proinsulin-Ab04
Product Name Anti-Equine Proinsulin human monoclonal antibody (mAb)
Target/Biomarker Equine Proinsulin ()
Alias of Target/Biomarker Equine Proinsulin
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with type 2 diabetes.
Tag hFc
Products description Anti-Equine Proinsulin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Equine Proinsulin, an intricate 86-amino acid peptide hormone, holds a pivotal position in the intricate web of insulin biosynthesis within horses. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initial steps in insulin biosynthesis. The journey of Horse Proinsulin commences with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide is a distinguishing feature of proinsulin and plays a significant role in insulin biosynthesis. During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it regulates glucose metabolism by facilitating glucose uptake into cells. The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. Research suggests that the C-peptide may possess independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

    Comments


    No comments yet.

    Leave a comment