Equine Proinsulin antibody and antigen (recombinant protein)
Diagnostic anti-Equine Proinsulin antibodies pairs and antigen for animal health (animal Equine/Horse type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-EQU-Proinsulin-Ag01 | Equine Proinsulin | $3090.00 |
GMP-EQU-Proinsulin-Ab01 | Anti-Equine Proinsulin mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-Proinsulin-Ab02 | Anti-Equine Proinsulin mouse monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-Proinsulin-Ab03 | Anti-Equine Proinsulin human monoclonal antibody (mAb) | $3090.00 |
GMP-EQU-Proinsulin-Ab04 | Anti-Equine Proinsulin human monoclonal antibody (mAb) | $3090.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. | GMP-EQU-Proinsulin-Ag01 |
Product Name | Equine Proinsulin |
Target/Biomarker | Equine Proinsulin |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Equine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Proinsulin level test of animal Equine/Horse with type 2 diabetes. |
Tag | His | Reconized/Reactive Specics | Equine Proinsulin |
Product description | Recombinant Equine Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-Proinsulin-Ab01,GMP-EQU-Proinsulin-Ab02 |
Target/Biomarker | Equine Proinsulin |
Product Name | Anti-Equine Proinsulin mouse monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies in Equine Proinsulin level test of animal Equine/Horse with type 2 diabetes. |
Product description | Anti-Equine Proinsulin mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. | GMP-EQU-Proinsulin-Ab03,GMP-EQU-Proinsulin-Ab04 |
Target/Biomarker | Equine Proinsulin |
Product Name | Anti-Equine Proinsulin human monoclonal antibody (mAb) |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Recombinant Equine Proinsulin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Proinsulin antibodies in Equine Proinsulin level test of animal Equine/Horse with type 2 diabetes. |
Product description | Anti-Equine Proinsulin mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Equine Proinsulin, an intricate 86-amino acid peptide hormone, holds a pivotal position in the intricate web of insulin biosynthesis within horses. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initial steps in insulin biosynthesis.
The journey of Horse Proinsulin commences with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide is a distinguishing feature of proinsulin and plays a significant role in insulin biosynthesis.
During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it regulates glucose metabolism by facilitating glucose uptake into cells.
The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. Research suggests that the C-peptide may possess independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.
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