Equine Pancreatic elastase (PE-1) antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-Pancreatic-elastase-Ag01	Recombinant Equine Pancreatic elastase (PE-1) protein	3090
GMP-EQU-Pancreatic-elastase-Ab01	Anti-Equine Pancreatic elastase (PE-1) mouse monoclonal antibody (mAb)	1953
GMP-EQU-Pancreatic-elastase-Ab02	Anti-Equine Pancreatic elastase (PE-1) mouse monoclonal antibody (mAb)	1953
GMP-EQU-Pancreatic-elastase-Ab03	Anti-Equine Pancreatic elastase (PE-1) human monoclonal antibody (mAb)	1953
GMP-EQU-Pancreatic-elastase-Ab04	Anti-Equine Pancreatic elastase (PE-1) human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-Pancreatic-elastase-Ag01
Product Name	Recombinant Equine Pancreatic elastase (PE-1) protein
Target/Biomarker	Equine Pancreatic Elastase ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Pancreatic Elastase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Equine/Horse with pancreatitis.
Tag	His
Products description	Recombinant Equine Pancreatic elastase (PE-1) protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-Pancreatic-elastase-Ab01, GMP-EQU-Pancreatic-elastase-Ab02
Product Name	Anti-Equine Pancreatic elastase (PE-1) mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Pancreatic Elastase ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Pancreatic Elastase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with pancreatitis.
Tag	mFc
Products description	Anti-Equine Pancreatic elastase (PE-1) mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-Pancreatic-elastase-Ab03, GMP-EQU-Pancreatic-elastase-Ab04
Product Name	Anti-Equine Pancreatic elastase (PE-1) human monoclonal antibody (mAb)
Target/Biomarker	Equine Pancreatic Elastase ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Pancreatic Elastase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with pancreatitis.
Tag	hFc
Products description	Anti-Equine Pancreatic elastase (PE-1) human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Pancreatic Elastase, an enzymatic workhorse produced by the exocrine pancreas, occupies a pivotal role in the intricate symphony of protein digestion. Structurally, it belongs to the serine protease family, characterized by a catalytic triad composed of serine, histidine, and aspartate residues. The active site of pancreatic elastase is finely tuned to cleave peptide bonds adjacent to small, hydrophobic amino acids, making it particularly suited for its primary substrate, elastin. Elastin, a structural protein, bestows elasticity upon various connective tissues, including arteries, skin, and organs. The digestion of elastin and other proteins is catalyzed by pancreatic elastase, which cleaves these macromolecules into smaller, more manageable peptide fragments. This process is instrumental in breaking down dietary proteins into amino acids, the building blocks of life, enabling their absorption in the small intestine. Pancreatic elastase's release into the duodenum and upper jejunum of the small intestine is meticulously regulated in response to hormonal signals, ensuring that it is deployed precisely when needed during the digestive process. The measurement of pancreatic elastase levels offers a glimpse into the pancreas's exocrine function. A decrease in pancreatic elastase levels below the normative range signifies impaired pancreatic function and a compromised ability to digest proteins. This can lead to the malabsorption of essential nutrients and the development of clinical symptoms associated with protein deficiency.

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