Equine PTH antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-EQU-PTH-Ag01	Recombinant Equine PTH protein	3090
GMP-EQU-PTH-Ab01	Anti-Equine PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-EQU-PTH-Ab02	Anti-Equine PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-EQU-PTH-Ab03	Anti-Equine PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-EQU-PTH-Ab04	Anti-Equine PTH mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-EQU-PTH-Ag01
Product Name	Recombinant Equine PTH protein
Target/Biomarker	Equine parathyroid hormone (PTH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine parathyroid hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Equine/Horse with Hyperparathyroidism.
Tag	His
Products description	Recombinant Equine PTH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PTH-Ab01, GMP-EQU-PTH-Ab02, GMP-EQU-PTH-Ab03, GMP-EQU-PTH-Ab04
Product Name	Anti-Equine PTH mouse monoclonal antibody (mAb)
Target/Biomarker	Equine parathyroid hormone (PTH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Equine parathyroid hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PTH level test of animal Equine/Horse with Hyperparathyroidism.
Tag	mFc
Products description	Anti-Equine PTH mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Within the intricate world of equine physiology, Equine Parathyroid Hormone (ePTH) stands as a sentinel, orchestrating the equilibrium of calcium and phosphate, fundamental to the well-being of horses. Structurally, it is a single-chain polypeptide hormone composed of 84 amino acids, primarily synthesized and secreted by the parathyroid glands, small structures nestled near the thyroid gland. The core function of ePTH lies in its responsiveness to deviations in ionized calcium levels within the equine bloodstream. When blood calcium levels dip below the optimal range, specialized calcium-sensing receptors within the parathyroid glands detect this perturbation and trigger the secretion of ePTH. ePTH, once released into circulation, embarks on a multi-faceted mission to restore calcium balance. Its primary target is the equine skeleton. Here, ePTH activates osteoclasts, specialized cells responsible for bone resorption. This process involves the breakdown of bone tissue, releasing stored calcium into the bloodstream. Simultaneously, ePTH enhances the reabsorption of calcium from urine in the kidneys, conserving this vital mineral. Furthermore, ePTH extends its influence to the gastrointestinal system by promoting the synthesis of calcitriol, the active form of vitamin D. Calcitriol, in turn, amplifies the absorption of dietary calcium in the equine intestines, completing the intricate loop of calcium regulation.

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