Equine PINP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-PINP-Ag01	Recombinant Equine PINP protein	3090
GMP-EQU-PINP-Ab01	Anti-Equine PINP mouse monoclonal antibody (mAb)	1953
GMP-EQU-PINP-Ab02	Anti-Equine PINP mouse monoclonal antibody (mAb)	1953
GMP-EQU-PINP-Ab03	Anti-Equine PINP human monoclonal antibody (mAb)	1953
GMP-EQU-PINP-Ab04	Anti-Equine PINP human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-PINP-Ag01
Product Name	Recombinant Equine PINP protein
Target/Biomarker	Equine amino-terminal propeptide (PINP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine amino-terminal propeptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of animal Equine/Horse with osteoporosis therapy.
Tag	His
Products description	Recombinant Equine PINP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PINP-Ab01, GMP-EQU-PINP-Ab02
Product Name	Anti-Equine PINP mouse monoclonal antibody (mAb)
Target/Biomarker	Equine amino-terminal propeptide (PINP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine amino-terminal propeptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PINP antibodies in PINP level test of animal Equine/Horse with osteoporosis therapy.
Tag	mFc
Products description	Anti-Equine PINP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PINP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PINP-Ab03, GMP-EQU-PINP-Ab04
Product Name	Anti-Equine PINP human monoclonal antibody (mAb)
Target/Biomarker	Equine amino-terminal propeptide (PINP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine amino-terminal propeptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PINP antibodies in PINP level test of animal Equine/Horse with osteoporosis therapy.
Tag	hFc
Products description	Anti-Equine PINP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PINP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Procollagen Type I N-Terminal Propeptide (PINP) stands as a sentinel in the intricate domain of equine physiology, offering a microscopic glimpse into the ever-evolving tapestry of collagen synthesis and bone metabolism in horses. At its core, PINP represents a fragment of the precursor protein procollagen type I, a linchpin in collagen biosynthesis. Structurally, procollagen type I comprises two proα1(I) chains and one proα2(I) chain, meticulously interwoven to form a triple helix. PINP, residing at the N-terminal end of the proα1(I) chain, plays a pivotal role in the continuum of collagen assembly in equines. The significance of PINP lies in its ability to mirror the dynamic processes of bone formation and remodeling in horses. As bones undergo constant renewal, procollagen type I is synthesized and subsequently cleaved, yielding mature collagen fibrils. PINP, released into the bloodstream during these transformations, offers a tangible gauge of collagen turnover, especially within the context of equine skeletal tissue.

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