Equine PG II antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-PG-II-Ag01	Recombinant Equine PG II protein	3090
GMP-EQU-PG-II-Ab01	Anti-Equine PG II mouse monoclonal antibody (mAb)	1953
GMP-EQU-PG-II-Ab02	Anti-Equine PG II mouse monoclonal antibody (mAb)	1953
GMP-EQU-PG-II-Ab03	Anti-Equine PG II human monoclonal antibody (mAb)	1953
GMP-EQU-PG-II-Ab04	Anti-Equine PG II human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-PG-II-Ag01
Product Name	Recombinant Equine PG II protein
Target/Biomarker	Equine Pepsinogen Ii (PG II)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Pepsinogen Ii antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of animal Equine/Horse with pernicious anemia.
Tag	His
Products description	Recombinant Equine PG II protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PG-II-Ab01, GMP-EQU-PG-II-Ab02
Product Name	Anti-Equine PG II mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Pepsinogen Ii (PG II)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Pepsinogen Ii antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG II antibodies in PG II level test of animal Equine/Horse with pernicious anemia.
Tag	mFc
Products description	Anti-Equine PG II mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG II antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PG-II-Ab03, GMP-EQU-PG-II-Ab04
Product Name	Anti-Equine PG II human monoclonal antibody (mAb)
Target/Biomarker	Equine Pepsinogen Ii (PG II)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Pepsinogen Ii antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG II antibodies in PG II level test of animal Equine/Horse with pernicious anemia.
Tag	hFc
Products description	Anti-Equine PG II human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG II antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine/Horse Pepsinogen II (PG II) emerges as a captivating biomarker, offering profound insights into the intricacies of equine digestion. Structurally, PG II is an inactive zymogen, a precursor to the active enzyme pepsin, and it assumes a central role within the gastric mucosa of the horse's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands. The journey of PG II begins with the intake of food. As dietary proteins enter the horse's stomach, PG II stands ready for its transformation into active pepsin. This metamorphosis unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG II to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall equine health. Beyond its role as a digestive precursor, PG II serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG II is predominantly localized, is pivotal for its proper secretion. Disruptions in this mucosal lining, as observed in conditions like gastric ulcers, gastritis, or gastric glandular disease, can lead to alterations in PG II levels, offering valuable diagnostic insights.

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