Equine PG II antibody and antigen (recombinant protein)

Diagnostic anti-Equine PG II antibodies pairs and antigen for animal health (animal Equine/Horse pernicious anemia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-PG-II-Ag01Equine PG II$3090.00
GMP-EQU-PG-II-Ab01Anti-Equine PG II mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-II-Ab02Anti-Equine PG II mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-II-Ab03Anti-Equine PG II human monoclonal antibody (mAb)$3090.00
GMP-EQU-PG-II-Ab04Anti-Equine PG II human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-PG-II-Ag01
Product NameEquine PG II
Target/BiomarkerEquine PG II
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine PG II antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG II level test of animal Equine/Horse with pernicious anemia.
TagHis
Reconized/Reactive SpecicsEquine PG II
Product descriptionRecombinant Equine PG II protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PG-II-Ab01,GMP-EQU-PG-II-Ab02
Target/BiomarkerEquine PG II
Product NameAnti-Equine PG II mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine PG II antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG II antibodies in Equine PG II level test of animal Equine/Horse with pernicious anemia.
Product descriptionAnti-Equine PG II mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG II antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-PG-II-Ab03,GMP-EQU-PG-II-Ab04
Target/BiomarkerEquine PG II
Product NameAnti-Equine PG II human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine PG II antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine PG II antibodies in Equine PG II level test of animal Equine/Horse with pernicious anemia.
Product descriptionAnti-Equine PG II mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine/Horse Pepsinogen II (PG II) emerges as a captivating biomarker, offering profound insights into the intricacies of equine digestion. Structurally, PG II is an inactive zymogen, a precursor to the active enzyme pepsin, and it assumes a central role within the gastric mucosa of the horse's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands.

    The journey of PG II begins with the intake of food. As dietary proteins enter the horse's stomach, PG II stands ready for its transformation into active pepsin. This metamorphosis unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG II to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall equine health.

    Beyond its role as a digestive precursor, PG II serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG II is predominantly localized, is pivotal for its proper secretion. Disruptions in this mucosal lining, as observed in conditions like gastric ulcers, gastritis, or gastric glandular disease, can lead to alterations in PG II levels, offering valuable diagnostic insights.



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    GDU

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