Equine PG I antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-PG-I-Ag01	Recombinant Equine PG I protein	3090
GMP-EQU-PG-I-Ab01	Anti-Equine PG I mouse monoclonal antibody (mAb)	1953
GMP-EQU-PG-I-Ab02	Anti-Equine PG I mouse monoclonal antibody (mAb)	1953
GMP-EQU-PG-I-Ab03	Anti-Equine PG I human monoclonal antibody (mAb)	1953
GMP-EQU-PG-I-Ab04	Anti-Equine PG I human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-EQU-PG-I-Ag01
Product Name	Recombinant Equine PG I protein
Target/Biomarker	Equine pepsinogen I (PG I)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine pepsinogen I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	His
Products description	Recombinant Equine PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PG-I-Ab01, GMP-EQU-PG-I-Ab02
Product Name	Anti-Equine PG I mouse monoclonal antibody (mAb)
Target/Biomarker	Equine pepsinogen I (PG I)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine pepsinogen I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies in PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	mFc
Products description	Anti-Equine PG I mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-PG-I-Ab03, GMP-EQU-PG-I-Ab04
Product Name	Anti-Equine PG I human monoclonal antibody (mAb)
Target/Biomarker	Equine pepsinogen I (PG I)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine pepsinogen I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies in PG I level test of animal Equine/Horse with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	hFc
Products description	Anti-Equine PG I human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Equine/Horse Pepsinogen I (PG I) emerges as a captivating biomarker, offering a profound glimpse into the intricacies of equine digestion. Structurally, PG I is an inactive zymogen, a precursor to the active enzyme pepsin, and it assumes a central role within the gastric mucosa of the horse's stomach. This biomolecule is primarily produced and secreted by chief cells, specialized secretory cells nestled within the gastric glands. The journey of PG I begins with the intake of food. As dietary proteins enter the horse's stomach, PG I stands ready for its metamorphosis into pepsin. This transformation unfolds within the acidic milieu of the gastric lumen, catalyzed by the low pH. The conversion of PG I to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall equine health. Beyond its role as a digestive precursor, PG I serves as a barometer for gastric health. The integrity of the gastric mucosa, where PG I is predominantly localized, is crucial for its proper secretion. Disruptions in this mucosal lining, such as those seen in gastric ulcers or gastritis, can alter PG I levels, offering valuable diagnostic insights.

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