Equine NFL antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-NFL-Ag01	Recombinant Equine NFL protein	3090
GMP-EQU-NFL-Ab01	Anti-Equine NFL mouse monoclonal antibody (mAb)	1953
GMP-EQU-NFL-Ab02	Anti-Equine NFL mouse monoclonal antibody (mAb)	1953
GMP-EQU-NFL-Ab03	Anti-Equine NFL human monoclonal antibody (mAb)	1953
GMP-EQU-NFL-Ab04	Anti-Equine NFL human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-NFL-Ag01
Product Name	Recombinant Equine NFL protein
Target/Biomarker	Equine Neurofilament Light Chain (NFL)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Neurofilament Light Chain antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NFL level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Equine NFL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-NFL-Ab01, GMP-EQU-NFL-Ab02
Product Name	Anti-Equine NFL mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Neurofilament Light Chain (NFL)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Neurofilament Light Chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies in NFL level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Equine NFL mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-NFL-Ab03, GMP-EQU-NFL-Ab04
Product Name	Anti-Equine NFL human monoclonal antibody (mAb)
Target/Biomarker	Equine Neurofilament Light Chain (NFL)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Neurofilament Light Chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies in NFL level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Equine NFL human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Neurofilament Light Chain (NFL) emerges as a remarkable molecule in equine neurobiology, assuming a central role in maintaining neuronal integrity and offering insights into the neurological health of horses. Structurally, NFL belongs to the neurofilament protein family and predominantly resides within the axons of equine neurons. Its filamentous nature equips it with the capacity to bolster neuronal structural integrity, specifically within axons, and facilitate the efficient transmission of electrical signals. The significance of NFL is accentuated in scenarios involving neuronal injury or degeneration. When equine neurons sustain damage, be it from traumatic events, neurodegenerative conditions, or inflammatory processes, NFL is released from the affected axons. These liberated NFL molecules eventually find their way into the cerebrospinal fluid (CSF) and bloodstream, endowing NFL with the status of a measurable biomarker for neuronal damage. This characteristic release pattern positions NFL as a valuable asset for the diagnosis and monitoring of neurological conditions in horses.

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