Equine MPO antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-MPO-Ag01	Recombinant Equine MPO protein	3090
GMP-EQU-MPO-Ab01	Anti-Equine MPO mouse monoclonal antibody (mAb)	1953
GMP-EQU-MPO-Ab02	Anti-Equine MPO mouse monoclonal antibody (mAb)	1953
GMP-EQU-MPO-Ab03	Anti-Equine MPO human monoclonal antibody (mAb)	1953
GMP-EQU-MPO-Ab04	Anti-Equine MPO human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-MPO-Ag01
Product Name	Recombinant Equine MPO protein
Target/Biomarker	Equine Myeloperoxidase (MPO)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Myeloperoxidase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MPO level test of animal Equine/Horse with vascular inflammation.
Tag	His
Products description	Recombinant Equine MPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-MPO-Ab01, GMP-EQU-MPO-Ab02
Product Name	Anti-Equine MPO mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Myeloperoxidase (MPO)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Myeloperoxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MPO antibodies in MPO level test of animal Equine/Horse with vascular inflammation.
Tag	mFc
Products description	Anti-Equine MPO mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MPO antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-MPO-Ab03, GMP-EQU-MPO-Ab04
Product Name	Anti-Equine MPO human monoclonal antibody (mAb)
Target/Biomarker	Equine Myeloperoxidase (MPO)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Myeloperoxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MPO antibodies in MPO level test of animal Equine/Horse with vascular inflammation.
Tag	hFc
Products description	Anti-Equine MPO human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MPO antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Myeloperoxidase (MPO) in horses, often referred to as an indispensable enzymatic component of the innate immune system, is primarily located within the neutrophils, a specialized subset of white blood cells. Neutrophils are the body's rapid response team against invading pathogens, and MPO plays an instrumental role in their antimicrobial arsenal. Structurally, MPO is a heme-containing enzyme, featuring iron atoms at its core. When neutrophils detect the presence of microbial threats, they deploy MPO into the surrounding environment as part of the immune defense. MPO's primary mission is to catalyze the conversion of hydrogen peroxide (H2O2) and chloride ions (Cl-) into hypochlorous acid (HOCl). HOCl is a highly potent and reactive antimicrobial agent, capable of rapidly neutralizing a diverse array of microorganisms, including bacteria, fungi, and viruses. MPO's antimicrobial prowess is multifaceted. It generates reactive oxygen species (ROS), such as superoxide radicals and hydrogen peroxide, which are toxic to pathogens. Additionally, it promotes the conversion of chloride ions into hypochlorous acid, further enhancing the neutrophils' ability to eliminate invaders.

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