Equine MOG antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-MOG-Ag01	Recombinant Equine MOG protein	3090
GMP-EQU-MOG-Ab01	Anti-Equine MOG mouse monoclonal antibody (mAb)	1953
GMP-EQU-MOG-Ab02	Anti-Equine MOG mouse monoclonal antibody (mAb)	1953
GMP-EQU-MOG-Ab03	Anti-Equine MOG human monoclonal antibody (mAb)	1953
GMP-EQU-MOG-Ab04	Anti-Equine MOG human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-MOG-Ag01
Product Name	Recombinant Equine MOG protein
Target/Biomarker	Equine myelin oligodendrocyte glycoprotein (MOG)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine myelin oligodendrocyte glycoprotein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MOG level test of animal Equine/Horse with MOG antibody disease.
Tag	His
Products description	Recombinant Equine MOG protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-MOG-Ab01, GMP-EQU-MOG-Ab02
Product Name	Anti-Equine MOG mouse monoclonal antibody (mAb)
Target/Biomarker	Equine myelin oligodendrocyte glycoprotein (MOG)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine myelin oligodendrocyte glycoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MOG antibodies in MOG level test of animal Equine/Horse with MOG antibody disease.
Tag	mFc
Products description	Anti-Equine MOG mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MOG antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-MOG-Ab03, GMP-EQU-MOG-Ab04
Product Name	Anti-Equine MOG human monoclonal antibody (mAb)
Target/Biomarker	Equine myelin oligodendrocyte glycoprotein (MOG)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine myelin oligodendrocyte glycoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MOG antibodies in MOG level test of animal Equine/Horse with MOG antibody disease.
Tag	hFc
Products description	Anti-Equine MOG human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MOG antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Myelin Oligodendrocyte Glycoprotein (MOG) in horses represents a pivotal component of the central nervous system (CNS), where its role in maintaining the integrity of the myelin sheath and its potential involvement in immune regulation within the CNS have garnered significant scientific interest. MOG is a glycoprotein primarily localized on the surface of oligodendrocytes, specialized glial cells tasked with the production of the myelin sheath. This sheath serves as an insulating layer around nerve fibers, enabling efficient conduction of electrical signals along neurons. MOG's presence on oligodendrocytes is essential for the adhesion between the myelin sheath and the underlying axons, ensuring structural stability and the preservation of nerve function. Within the context of the immune system, MOG's role is multifaceted and not fully elucidated. It is believed to participate in immune regulation within the CNS, contributing to the maintenance of immune tolerance. However, under certain conditions, such as autoimmune responses, MOG can become a target of the immune system, leading to the production of autoantibodies against MOG. In horses, as in other vertebrates, MOG is critical for the normal functioning of the CNS. Its role in facilitating rapid nerve signal transmission and its involvement in immune processes highlight its significance in equine neurological health.

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