Equine LN antibody and antigen (recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-LN-Ag01	Recombinant Equine LN protein	3090
GMP-EQU-LN-Ab01	Anti-Equine LN mouse monoclonal antibody (mAb)	1953
GMP-EQU-LN-Ab02	Anti-Equine LN mouse monoclonal antibody (mAb)	1953
GMP-EQU-LN-Ab03	Anti-Equine LN human monoclonal antibody (mAb)	1953
GMP-EQU-LN-Ab04	Anti-Equine LN human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-LN-Ag01
Product Name	Recombinant Equine LN protein
Target/Biomarker	Equine laminins (LN)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine laminins antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in LN level test of animal Equine/Horse with muscular dystrophy, lethal skin blistering disease (junctional epidermolysis bullosa) and nephrotic syndrome.
Tag	His
Products description	Recombinant Equine LN protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-LN-Ab01, GMP-EQU-LN-Ab02
Product Name	Anti-Equine LN mouse monoclonal antibody (mAb)
Target/Biomarker	Equine laminins (LN)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine laminins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-LN antibodies in LN level test of animal Equine/Horse with muscular dystrophy, lethal skin blistering disease (junctional epidermolysis bullosa) and nephrotic syndrome.
Tag	mFc
Products description	Anti-Equine LN mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-LN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-LN-Ab03, GMP-EQU-LN-Ab04
Product Name	Anti-Equine LN human monoclonal antibody (mAb)
Target/Biomarker	Equine laminins (LN)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine laminins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-LN antibodies in LN level test of animal Equine/Horse with muscular dystrophy, lethal skin blistering disease (junctional epidermolysis bullosa) and nephrotic syndrome.
Tag	hFc
Products description	Anti-Equine LN human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-LN antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

The Equine Lymph Node (eLN) stands as a sentinel in the complex network of equine immunity, an unsung hero safeguarding a horse's health. Positioned strategically in various anatomical regions, the eLN tirelessly monitors the horse's interstitial fluid, capturing antigens, and orchestrating immune defenses with precision and expertise. Structurally, the eLN is an encapsulated organ, enclosed by a fibrous tissue known as the capsule. This capsule houses a labyrinth of lymphatic sinuses and nodules where immune cells reside and interact. Within these microenvironments, immune cells are stationed, primed to detect and respond to potential threats. Among these immune cells, lymphocytes, the primary players of adaptive immunity, abound. T cells and B cells, distinct lymphocyte subsets, collaborate to recognize and target specific antigens, while macrophages act as the body's professional scavengers, clearing cellular debris and engulfing foreign invaders. When antigens enter the lymphatic fluid, either through infection or other means, a series of events unfolds within the eLN. Antigen-presenting cells, including dendritic cells, encounter these antigens and capture them. They then migrate to the eLN, where they present the antigens to T cells. This presentation serves as a call to arms, activating T cells that recognize the specific antigen. B cells within the eLN also play a crucial role by producing antibodies that can neutralize invaders. The eLN, in essence, functions as a training ground for immune cells. It is where naïve lymphocytes are exposed to antigens, learn to differentiate self from non-self, and develop memory responses. This training is critical for the horse's ability to mount swift and specific immune defenses upon subsequent encounters with the same antigens.

About GDU