Equine HE4 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-HE4-Ag01	Recombinant Equine HE4 protein	3090
GMP-EQU-HE4-Ab01	Anti-Equine HE4 mouse monoclonal antibody (mAb)	1953
GMP-EQU-HE4-Ab02	Anti-Equine HE4 mouse monoclonal antibody (mAb)	1953
GMP-EQU-HE4-Ab03	Anti-Equine HE4 human monoclonal antibody (mAb)	1953
GMP-EQU-HE4-Ab04	Anti-Equine HE4 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-HE4-Ag01
Product Name	Recombinant Equine HE4 protein
Target/Biomarker	Equine epididymis protein 4 (HE4)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine epididymis protein 4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HE4 level test of animal Equine/Horse with ovarian cancer.
Tag	His
Products description	Recombinant Equine HE4 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-HE4-Ab01, GMP-EQU-HE4-Ab02
Product Name	Anti-Equine HE4 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Equine/Horse with ovarian cancer.
Tag	mFc
Products description	Anti-Equine HE4 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-HE4-Ab03, GMP-EQU-HE4-Ab04
Product Name	Anti-Equine HE4 human monoclonal antibody (mAb)
Target/Biomarker	Equine epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Equine/Horse with ovarian cancer.
Tag	hFc
Products description	Anti-Equine HE4 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

HE4, known scientifically as Human Epididymis Protein 4, is an emerging biomarker with substantial relevance in the field of equine health. Originating from its discovery in humans, HE4 has exhibited homologous counterparts in various species, prominently including horses. It assumes the form of a glycoprotein, primarily manifesting within the equine reproductive system, with specific localization in the epididymis and female reproductive organs.The role of HE4 in equine physiology is multifaceted and of growing interest. One of its critical functions lies in the regulation of ovarian activity. Expression levels of HE4 exhibit dynamic fluctuations during different phases of the estrous cycle, rendering it a pivotal indicator of reproductive status. Notably, this biomarker has also been associated with specific reproductive disorders, thereby serving as an invaluable tool for veterinarians and breeders in monitoring the reproductive health of mares and stallions. Beyond its role in reproduction, HE4 holds promise as a marker for various physiological processes in horses. Current research is actively investigating its involvement in immune system modulation and metabolic regulation. These studies suggest that HE4 may be intertwined with the broader health of equine individuals, extending its significance beyond the reproductive realm. As our comprehension of HE4 deepens, it may open doors to innovative diagnostic techniques and therapeutic interventions for diverse equine health conditions, transcending its initial characterization as a reproductive biomarker. The scientific exploration of HE4 in the equine context represents an exciting avenue for enhancing our understanding of equine biology, optimizing reproductive management, and potentially revolutionizing the diagnosis and treatment of equine health disorders.|

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