Equine H-FABP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-H-FABP-Ag01	Recombinant Equine H-FABP protein	3090
GMP-EQU-H-FABP-Ab01	Anti-Equine H-FABP mouse monoclonal antibody (mAb)	1953
GMP-EQU-H-FABP-Ab02	Anti-Equine H-FABP mouse monoclonal antibody (mAb)	1953
GMP-EQU-H-FABP-Ab03	Anti-Equine H-FABP human monoclonal antibody (mAb)	1953
GMP-EQU-H-FABP-Ab04	Anti-Equine H-FABP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-H-FABP-Ag01
Product Name	Recombinant Equine H-FABP protein
Target/Biomarker	Equine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Heart-type Fatty Acid-Binding Protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in H-FABP level test of animal Equine/Horse with myocardial injury.
Tag	His
Products description	Recombinant Equine H-FABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-H-FABP-Ab01, GMP-EQU-H-FABP-Ab02
Product Name	Anti-Equine H-FABP mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Heart-type Fatty Acid-Binding Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies in H-FABP level test of animal Equine/Horse with myocardial injury.
Tag	mFc
Products description	Anti-Equine H-FABP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-H-FABP-Ab03, GMP-EQU-H-FABP-Ab04
Product Name	Anti-Equine H-FABP human monoclonal antibody (mAb)
Target/Biomarker	Equine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Heart-type Fatty Acid-Binding Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies in H-FABP level test of animal Equine/Horse with myocardial injury.
Tag	hFc
Products description	Anti-Equine H-FABP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

H-FABP, or Heart-Fatty Acid Binding Protein, emerges as a pivotal biomarker in the intricate realm of equine (horse) physiology. This unassuming yet indispensable protein finds its primary expression within the heart muscle, or cardiomyocytes, where it orchestrates the regulation of fatty acid metabolism. Structurally, H-FABP is a cytoplasmic protein adorned with a distinct binding pocket that enables it to transport and facilitate the utilization of fatty acids—a fundamental energy source—within the equine cardiac muscle cells. The exclusive residence of H-FABP within the equine heart underscores its crucial role in assessing cardiac health. Under normal physiological circumstances, H-FABP levels in the bloodstream of horses remain relatively low. However, its concentration can surge significantly in response to cardiac stress or injury, rendering it a highly sensitive and specific diagnostic tool for veterinarians and a source of invaluable insights for equine enthusiasts. H-FABP's functional significance within the heart extends beyond its metabolic role. It is when the equine heart faces challenges that the true importance of H-FABP as a biomarker shines. In scenarios where cardiac ischemia or infarction occurs, such as a heart attack, a segment of the heart muscle becomes deprived of oxygen and nutrients due to a blocked artery. It is during this ischemic injury that H-FABP is released into the bloodstream. Consequently, elevated levels of H-FABP in a horse's blood can serve as an early indicator of myocardial damage, often preceding clinical symptoms. The rapid identification of such cardiac issues allows for prompt medical intervention, potentially limiting the extent of cardiac damage and enhancing the likelihood of a positive outcome.

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