Equine GFAP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-GFAP-Ag01	Recombinant Equine GFAP protein	3090
GMP-EQU-GFAP-Ab01	Anti-Equine GFAP mouse monoclonal antibody (mAb)	1953
GMP-EQU-GFAP-Ab02	Anti-Equine GFAP mouse monoclonal antibody (mAb)	1953
GMP-EQU-GFAP-Ab03	Anti-Equine GFAP human monoclonal antibody (mAb)	1953
GMP-EQU-GFAP-Ab04	Anti-Equine GFAP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-GFAP-Ag01
Product Name	Recombinant Equine GFAP protein
Target/Biomarker	Equine Glial fibrillary acid protein (GFAP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Glial fibrillary acid protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Equine GFAP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-GFAP-Ab01, GMP-EQU-GFAP-Ab02
Product Name	Anti-Equine GFAP mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Glial fibrillary acid protein (GFAP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Glial fibrillary acid protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GFAP antibodies in GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Equine GFAP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GFAP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-GFAP-Ab03, GMP-EQU-GFAP-Ab04
Product Name	Anti-Equine GFAP human monoclonal antibody (mAb)
Target/Biomarker	Equine Glial fibrillary acid protein (GFAP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Glial fibrillary acid protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GFAP antibodies in GFAP level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Equine GFAP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GFAP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine GFAP, Glial Fibrillary Acidic Protein, serves as a guardian within the intricate tapestry of equine neurobiology. This protein, predominantly residing within the astrocytes of the central nervous system (CNS) of horses, plays multifaceted roles in maintaining the structural and functional integrity of the nervous system. Structurally, Equine GFAP is a member of the intermediate filament protein family, sharing genetic and functional homology with its counterparts in diverse species, including humans. Astrocytes, the primary reservoir of GFAP, rely on this protein for structural support and cytoskeletal resilience. Equine GFAP filaments form an elaborate network within astrocytes, contributing to their adaptability and their ability to respond to various challenges. Functionally, Equine GFAP plays a pivotal role in supporting neuronal health. Astrocytes, by nourishing neurons, regulating synaptic transmission, and modulating neurotransmitter levels, are integral to CNS function. Equine GFAP actively participates in these processes, ensuring the optimal functioning of the equine CNS. However, the significance of Equine GFAP extends beyond these foundational roles. In response to CNS injury, neuroinflammation, or neurodegenerative conditions, astrocytes undergo a transformative process known as astrogliosis. During astrogliosis, astrocytes become activated, leading to increased expression of GFAP. This upregulation serves as a protective and reparative response, as astrocytes encapsulate injured areas, isolate toxic substances, and support neuronal recovery.

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