Equine GDF-15 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-GDF-15-Ag01	Recombinant Equine GDF-15 protein	3090
GMP-EQU-GDF-15-Ab01	Anti-Equine GDF-15 mouse monoclonal antibody (mAb)	1953
GMP-EQU-GDF-15-Ab02	Anti-Equine GDF-15 mouse monoclonal antibody (mAb)	1953
GMP-EQU-GDF-15-Ab03	Anti-Equine GDF-15 human monoclonal antibody (mAb)	1953
GMP-EQU-GDF-15-Ab04	Anti-Equine GDF-15 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-GDF-15-Ag01
Product Name	Recombinant Equine GDF-15 protein
Target/Biomarker	Equine Growth differentiation factor-15 (GDF-15)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Growth differentiation factor-15 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of animal Equine/Horse with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	His
Products description	Recombinant Equine GDF-15 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-GDF-15-Ab01, GMP-EQU-GDF-15-Ab02
Product Name	Anti-Equine GDF-15 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Growth differentiation factor-15 (GDF-15)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Growth differentiation factor-15 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies in GDF-15 level test of animal Equine/Horse with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	mFc
Products description	Anti-Equine GDF-15 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-GDF-15-Ab03, GMP-EQU-GDF-15-Ab04
Product Name	Anti-Equine GDF-15 human monoclonal antibody (mAb)
Target/Biomarker	Equine Growth differentiation factor-15 (GDF-15)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Growth differentiation factor-15 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies in GDF-15 level test of animal Equine/Horse with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	hFc
Products description	Anti-Equine GDF-15 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Growth Differentiation Factor 15 (GDF-15), also known as macrophage inhibitory cytokine 1 (MIC-1), stands as a multifaceted protein biomarker within the intricate landscape of equine biology. It belongs to the transforming growth factor-beta (TGF-β) superfamily and is secreted by various cell types in horses, including macrophages, cardiac myocytes, and adipocytes. Structurally, GDF-15 is a dimeric protein, consisting of two subunits held together by disulfide bonds. GDF-15 is a versatile regulator of cellular processes in horses, with a profound impact on equine physiology. It plays a pivotal role in modulating inflammation, controlling cell growth, and orchestrating apoptosis (programmed cell death). This multifunctional nature enables GDF-15 to respond dynamically to various stimuli, making it a crucial component of the equine immune response and overall health.

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