Equine D-Dimer antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-D-Dimer-Ag01	Recombinant Equine D-Dimer protein	3090
GMP-EQU-D-Dimer-Ab01	Anti-Equine D-Dimer mouse monoclonal antibody (mAb)	3090
GMP-EQU-D-Dimer-Ab02	Anti-Equine D-Dimer mouse monoclonal antibody (mAb)	3090
GMP-EQU-D-Dimer-Ab03	Anti-Equine D-Dimer human monoclonal antibody (mAb)	3090
GMP-EQU-D-Dimer-Ab04	Anti-Equine D-Dimer human monoclonal antibody (mAb)	3090

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-D-Dimer-Ag01
Product Name	Recombinant Equine D-Dimer protein
Target/Biomarker	Equine D Dimer (D-Dimer)
Alias of Target/Biomarker	Equine D Dimer (D-Dimer)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine D Dimer antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of animal Equine/Horse with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	His
Products description	Recombinant Equine D-Dimer protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-D-Dimer-Ab01, GMP-EQU-D-Dimer-Ab02
Product Name	Anti-Equine D-Dimer mouse monoclonal antibody (mAb)
Target/Biomarker	Equine D Dimer (D-Dimer)
Alias of Target/Biomarker	Equine D Dimer (D-Dimer)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine D Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies in D-Dimer level test of animal Equine/Horse with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	mFc
Products description	Anti-Equine D-Dimer mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-D-Dimer-Ab03, GMP-EQU-D-Dimer-Ab04
Product Name	Anti-Equine D-Dimer human monoclonal antibody (mAb)
Target/Biomarker	Equine D Dimer (D-Dimer)
Alias of Target/Biomarker	Equine D Dimer (D-Dimer)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine D Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies in D-Dimer level test of animal Equine/Horse with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	hFc
Products description	Anti-Equine D-Dimer human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Expanding further on the nature of D-Dimer in horses, it is important to understand that D-Dimer molecules are not directly involved in the clotting process but are instead byproducts of fibrinolysis. Fibrinolysis is a natural process that breaks down and dissolves clots once the need for them has passed. In equines, as in humans and other animals, plasmin plays a central role in this process by cleaving fibrin strands. As these strands are cleaved, D-Dimer fragments are released into the bloodstream. The presence of elevated D-Dimer levels in horses signifies that there is an ongoing breakdown of fibrin, indicating an active fibrinolytic response. This is often associated with clot formation, as the body tries to regulate and dissolve clots that may have formed in response to injury, infection, or other underlying health issues. Accurate measurement of D-Dimer levels in equines can help veterinarians pinpoint the source of clotting abnormalities and provide targeted treatment.

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