Equine CYFRA21-1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-CYFRA21-1-Ag01	Recombinant Equine CYFRA21-1 protein	3090
GMP-EQU-CYFRA21-1-Ab01	Anti-Equine CYFRA21-1 mouse monoclonal antibody (mAb)	1953
GMP-EQU-CYFRA21-1-Ab02	Anti-Equine CYFRA21-1 mouse monoclonal antibody (mAb)	1953
GMP-EQU-CYFRA21-1-Ab03	Anti-Equine CYFRA21-1 human monoclonal antibody (mAb)	1953
GMP-EQU-CYFRA21-1-Ab04	Anti-Equine CYFRA21-1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-CYFRA21-1-Ag01
Product Name	Recombinant Equine CYFRA21-1 protein
Target/Biomarker	Equine soluble fragment of cytokeratin-19 (CYFRA21-1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine soluble fragment of cytokeratin-19 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CYFRA21-1 level test of animal Equine/Horse with bronchopulmonary dysplasia.
Tag	His
Products description	Recombinant Equine CYFRA21-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CYFRA21-1-Ab01, GMP-EQU-CYFRA21-1-Ab02
Product Name	Anti-Equine CYFRA21-1 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine soluble fragment of cytokeratin-19 (CYFRA21-1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine soluble fragment of cytokeratin-19 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CYFRA21-1 antibodies in CYFRA21-1 level test of animal Equine/Horse with bronchopulmonary dysplasia.
Tag	mFc
Products description	Anti-Equine CYFRA21-1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CYFRA21-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CYFRA21-1-Ab03, GMP-EQU-CYFRA21-1-Ab04
Product Name	Anti-Equine CYFRA21-1 human monoclonal antibody (mAb)
Target/Biomarker	Equine soluble fragment of cytokeratin-19 (CYFRA21-1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine soluble fragment of cytokeratin-19 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CYFRA21-1 antibodies in CYFRA21-1 level test of animal Equine/Horse with bronchopulmonary dysplasia.
Tag	hFc
Products description	Anti-Equine CYFRA21-1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CYFRA21-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

CYFRA21-1, also known as Cytokeratin 19 Fragment 21-1 (CYFRA 21-1), is a biomarker of significant importance within the realm of horses (equines). This biomarker originates from cytokeratin 19, a structural protein that plays a pivotal role in maintaining the integrity of the cytoskeleton of epithelial cells. Epithelial cells are a fundamental component of various equine tissues, including the respiratory system. When these cells undergo pathological changes, such as injury or malignant transformation, CYFRA21-1 fragments can be released into the bloodstream, making it a valuable indicator of the health of the respiratory and epithelial systems in equines. At the molecular level, CYFRA21-1 consists of specific fragments of cytokeratin 19, with the 21-1 fragment being a notable component. These soluble protein fragments can be detected through blood tests. In healthy horses, CYFRA21-1 levels are typically low. However, when there is damage or malignancy in epithelial tissues, particularly in the lungs, the levels of CYFRA21-1 can significantly increase. This phenomenon makes CYFRA21-1 a crucial biomarker for assessing the health of the respiratory and epithelial systems in equines.

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