Equine CK-MB antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-CK-MB-Ag01	Recombinant Equine CK-MB protein	3090
GMP-EQU-CK-MB-Ab01	Anti-Equine CK-MB mouse monoclonal antibody (mAb)	1953
GMP-EQU-CK-MB-Ab02	Anti-Equine CK-MB mouse monoclonal antibody (mAb)	1953
GMP-EQU-CK-MB-Ab03	Anti-Equine CK-MB human monoclonal antibody (mAb)	1953
GMP-EQU-CK-MB-Ab04	Anti-Equine CK-MB human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-CK-MB-Ag01
Product Name	Recombinant Equine CK-MB protein
Target/Biomarker	Equine Creatine Kinase MB (ACE2/hFc)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Creatine Kinase MB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of animal Equine/Horse with Myocardial hypoxia.
Tag	His
Products description	Recombinant Equine CK-MB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CK-MB-Ab01, GMP-EQU-CK-MB-Ab02
Product Name	Anti-Equine CK-MB mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Creatine Kinase MB (ACE2/hFc)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Creatine Kinase MB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies in ACE2/hFc level test of animal Equine/Horse with Myocardial hypoxia.
Tag	mFc
Products description	Anti-Equine CK-MB mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CK-MB-Ab03, GMP-EQU-CK-MB-Ab04
Product Name	Anti-Equine CK-MB human monoclonal antibody (mAb)
Target/Biomarker	Equine Creatine Kinase MB (ACE2/hFc)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Creatine Kinase MB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies in ACE2/hFc level test of animal Equine/Horse with Myocardial hypoxia.
Tag	hFc
Products description	Anti-Equine CK-MB human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Creatine Kinase-MB (CK-MB) in horses assumes a pivotal role as an enzyme biomarker with specific relevance to equine cardiology. It represents a subtype of the enzyme creatine kinase (CK), which is integral to energy metabolism, particularly in tissues characterized by high-energy demands, such as skeletal and cardiac muscle. In equines, CK-MB is primarily situated within cardiac muscle cells, making it a highly specific marker for assessing cardiac health. It comprises various isoforms, with the cardiac isoform CK-MB being the dominant variant in equine hearts. This specific localization of CK-MB within cardiac muscle renders it an accurate indicator of myocardial status in horses. When the heart muscle in horses experiences injury or stress, CK-MB is released into the bloodstream, where it becomes quantifiable. This release mechanism forms the foundation for employing CK-MB as an indicator of myocardial damage in equines. The measurement of CK-MB levels plays a pivotal role in diagnosing various cardiac conditions and monitoring the response to treatment.

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