Equine CBS antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-CBS-Ag01	Recombinant Equine CBS protein	3090
GMP-EQU-CBS-Ab01	Anti-Equine CBS mouse monoclonal antibody (mAb)	1953
GMP-EQU-CBS-Ab02	Anti-Equine CBS mouse monoclonal antibody (mAb)	1953
GMP-EQU-CBS-Ab03	Anti-Equine CBS human monoclonal antibody (mAb)	1953
GMP-EQU-CBS-Ab04	Anti-Equine CBS human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-CBS-Ag01
Product Name	Recombinant Equine CBS protein
Target/Biomarker	Equine cystathionine-β-synthase (AGP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine cystathionine-β-synthase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AGP level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Equine CBS protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CBS-Ab01, GMP-EQU-CBS-Ab02
Product Name	Anti-Equine CBS mouse monoclonal antibody (mAb)
Target/Biomarker	Equine cystathionine-β-synthase (AGP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies in AGP level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Equine CBS mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CBS-Ab03, GMP-EQU-CBS-Ab04
Product Name	Anti-Equine CBS human monoclonal antibody (mAb)
Target/Biomarker	Equine cystathionine-β-synthase (AGP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies in AGP level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Equine CBS human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AGP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine C-reactive Protein (eCRP) stands as a cornerstone biomarker in the world of equine health, intricately woven into the fabric of the horse's immune response to inflammatory challenges. Structurally, eCRP is a pentameric protein, composed of five identical subunits, each boasting a molecular mass of approximately 25 kDa. Its synthesis primarily occurs in the hepatocytes of the liver, induced by pro-inflammatory cytokines, most notably interleukin-6 (IL-6). The hallmark of eCRP lies in its rapid response to inflammation. When a horse confronts infectious agents, injuries, or other inflammatory triggers, the liver promptly initiates the production of eCRP. This leads to a noticeable increase in its concentration within the bloodstream, making eCRP an invaluable sentinel biomarker, capable of detecting even subtle deviations from normal health in a horse. Functionally, eCRP serves as an acute-phase reactant, playing a pivotal role in the horse's innate immune system. It enhances opsonization and phagocytosis, bolstering the body's defenses against invading pathogens and damaged tissues. eCRP's contribution extends to the initiation of the complement cascade, further aiding in the removal of threats.

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