Equine CBL antibody and antigen (recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-CBL-Ag01	Recombinant Equine CBL protein	3090
GMP-EQU-CBL-Ab01	Anti-Equine CBL mouse monoclonal antibody (mAb)	1953
GMP-EQU-CBL-Ab02	Anti-Equine CBL mouse monoclonal antibody (mAb)	1953
GMP-EQU-CBL-Ab03	Anti-Equine CBL human monoclonal antibody (mAb)	1953
GMP-EQU-CBL-Ab04	Anti-Equine CBL human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-CBL-Ag01
Product Name	Recombinant Equine CBL protein
Target/Biomarker	Equine cystathionine-β-synthase enzyme ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine cystathionine-β-synthase enzyme antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Equine CBL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CBL-Ab01, GMP-EQU-CBL-Ab02
Product Name	Anti-Equine CBL mouse monoclonal antibody (mAb)
Target/Biomarker	Equine cystathionine-β-synthase enzyme ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine cystathionine-β-synthase enzyme antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Equine CBL mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CBL-Ab03, GMP-EQU-CBL-Ab04
Product Name	Anti-Equine CBL human monoclonal antibody (mAb)
Target/Biomarker	Equine cystathionine-β-synthase enzyme ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine cystathionine-β-synthase enzyme antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Equine/Horse with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Equine CBL human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Cobalamin, or Vitamin B12, is an intriguing biochemical cornerstone within the equine (horse) community. This water-soluble vitamin, represented by the biomarker CBL, plays a pivotal role in a plethora of metabolic pathways that are vital for equine health and vigor. Structurally, Vitamin B12 boasts a complex molecular arrangement with a central cobalt atom. This cobalt atom is the linchpin of Vitamin B12's biological activity, crucial for its role as a coenzyme in enzymatic reactions that are foundational to equine physiology. One of Vitamin B12's critical functions is its involvement in the metabolic conversion of methylmalonyl-CoA to succinyl-CoA, a process catalyzed by methylmalonyl-CoA mutase. This conversion is of immense significance, as it contributes to the metabolism of amino acids and fatty acids, which are essential for the energy production and overall cellular function in horses. Furthermore, Vitamin B12 actively participates in the conversion of homocysteine to methionine, a reaction catalyzed by methionine synthase. Methionine is a fundamental amino acid and serves as the precursor for protein synthesis, making it indispensable for equine growth and muscle development. Beyond these vital functions, Vitamin B12 is crucial for DNA synthesis in horses. It supports the production of thymidine, one of the four nucleotide building blocks of DNA. This role is pivotal for equine growth, tissue repair, and overall development. Vitamin B12's significance further extends to the synthesis of myelin, the insulating sheath that envelops nerve fibers. In doing so, it ensures the efficient transmission of nerve impulses, underpinning neurological function. Additionally, Vitamin B12 plays a key role in heme synthesis, a vital component of hemoglobin within red blood cells. Hemoglobin's function in oxygen transport makes it central to equine vitality and performance.

About GDU