Equine CA15-3 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-CA15-3-Ag01	Recombinant Equine CA15-3 protein	3090
GMP-EQU-CA15-3-Ab01	Anti-Equine CA15-3 mouse monoclonal antibody (mAb)	1953
GMP-EQU-CA15-3-Ab02	Anti-Equine CA15-3 mouse monoclonal antibody (mAb)	1953
GMP-EQU-CA15-3-Ab03	Anti-Equine CA15-3 human monoclonal antibody (mAb)	1953
GMP-EQU-CA15-3-Ab04	Anti-Equine CA15-3 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-CA15-3-Ag01
Product Name	Recombinant Equine CA15-3 protein
Target/Biomarker	Equine Cancer antigen 15-3 (IBV - Variant 02)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Cancer antigen 15-3 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IBV - Variant 02 level test of animal Equine/Horse with breast cancer.
Tag	His
Products description	Recombinant Equine CA15-3 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CA15-3-Ab01, GMP-EQU-CA15-3-Ab02
Product Name	Anti-Equine CA15-3 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Cancer antigen 15-3 (IBV - Variant 02)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Cancer antigen 15-3 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 02 antibodies in IBV - Variant 02 level test of animal Equine/Horse with breast cancer.
Tag	mFc
Products description	Anti-Equine CA15-3 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 02 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-CA15-3-Ab03, GMP-EQU-CA15-3-Ab04
Product Name	Anti-Equine CA15-3 human monoclonal antibody (mAb)
Target/Biomarker	Equine Cancer antigen 15-3 (IBV - Variant 02)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Cancer antigen 15-3 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 02 antibodies in IBV - Variant 02 level test of animal Equine/Horse with breast cancer.
Tag	hFc
Products description	Anti-Equine CA15-3 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-IBV - Variant 02 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cancer Antigen 15-3 (CA15-3) is a biomarker with significant relevance in the realm of equine biology. Originally characterized in humans, CA15-3 has homologous counterparts in various species, including horses. This glycoprotein assumes a pivotal role in equine physiology, particularly in the context of mammary tissue development and health. In mares and potentially in geldings, CA15-3 takes center stage within the intricate landscape of mammary gland physiology. The mammary glands play a critical role in the reproductive biology of mares, serving the essential function of providing nourishment to foals during lactation. Consequently, any disturbances or abnormalities in mammary gland health can have profound implications for equine reproductive capacity and overall well-being. CA15-3 is a biomarker that exhibits dynamic expression patterns within the mammary glands of horses. Its levels can vary in response to various physiological factors and changes during different stages of the reproductive cycle, including pregnancy and lactation. These dynamic expressions are closely linked to the regulation of mammary tissue development and function, making CA15-3 a sentinel for the health and integrity of this vital tissue. Furthermore, CA15-3 in horses is of particular interest due to its association with mammary tumors, a condition that can affect both mares and geldings. Mammary tumors in horses can vary widely in their characteristics, from benign to malignant, and their early detection and diagnosis are pivotal for timely intervention and improved treatment outcomes. CA15-3 levels have shown promise as a diagnostic tool, with elevated levels often correlating with the presence of mammary tumors and their potential malignancy.

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