Equine ApoE antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-ApoE-Ag01	Recombinant Equine ApoE protein	3090
GMP-EQU-ApoE-Ab01	Anti-Equine ApoE mouse monoclonal antibody (mAb)	1953
GMP-EQU-ApoE-Ab02	Anti-Equine ApoE mouse monoclonal antibody (mAb)	1953
GMP-EQU-ApoE-Ab03	Anti-Equine ApoE human monoclonal antibody (mAb)	1953
GMP-EQU-ApoE-Ab04	Anti-Equine ApoE human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-ApoE-Ag01
Product Name	Recombinant Equine ApoE protein
Target/Biomarker	Equine Apolipoprotein E (CAV)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Apolipoprotein E antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CAV level test of animal Equine/Horse with Cardiovascular Disease.
Tag	His
Products description	Recombinant Equine ApoE protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-ApoE-Ab01, GMP-EQU-ApoE-Ab02
Product Name	Anti-Equine ApoE mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Apolipoprotein E (CAV)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Apolipoprotein E antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CAV antibodies in CAV level test of animal Equine/Horse with Cardiovascular Disease.
Tag	mFc
Products description	Anti-Equine ApoE mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CAV antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-ApoE-Ab03, GMP-EQU-ApoE-Ab04
Product Name	Anti-Equine ApoE human monoclonal antibody (mAb)
Target/Biomarker	Equine Apolipoprotein E (CAV)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Apolipoprotein E antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CAV antibodies in CAV level test of animal Equine/Horse with Cardiovascular Disease.
Tag	hFc
Products description	Anti-Equine ApoE human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CAV antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine Apolipoprotein E, often referred to as Equine ApoE, is a multifaceted protein that occupies a central role in the intricate domain of equine physiology. Predominantly synthesized in the liver of domestic horses (Equus ferus caballus), this glycoprotein exhibits a unique structural feature marked by carbohydrates attached to its polypeptide chain. As a distinguished member of the apolipoprotein family, Equine ApoE orchestrates a complex symphony of lipid metabolism, with a particular emphasis on cholesterol management within the equine body. The prominence of Equine ApoE comes to the forefront in its association with high-density lipoproteins (HDL), commonly hailed as "good cholesterol." HDL particles, acting as custodians of cholesterol and lipids in the equine bloodstream, rely significantly on Equine ApoE for their structural integrity and functional prowess. This biomarker serves as an integral component of HDLs, contributing not only to their structural integrity but also to their dynamic role in the reverse cholesterol transport pathway. The choreography of cholesterol transport begins with Equine ApoE. It binds to lipids, effectively transforming nascent HDL particles into active carriers of excess cholesterol. These HDLs embark on a journey to peripheral tissues, where they retrieve surplus cholesterol and lipids, subsequently venturing back to the liver. In the liver, cholesterol undergoes metabolism and eventual excretion, ensuring the maintenance of optimal cholesterol levels within the equine body.

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