Equine ACRV1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-EQU-ACRV1-Ag01	Recombinant Equine ACRV1 protein	3090
GMP-EQU-ACRV1-Ab01	Anti-Equine ACRV1 mouse monoclonal antibody (mAb)	1953
GMP-EQU-ACRV1-Ab02	Anti-Equine ACRV1 mouse monoclonal antibody (mAb)	1953
GMP-EQU-ACRV1-Ab03	Anti-Equine ACRV1 human monoclonal antibody (mAb)	1953
GMP-EQU-ACRV1-Ab04	Anti-Equine ACRV1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-EQU-ACRV1-Ag01
Product Name	Recombinant Equine ACRV1 protein
Target/Biomarker	Equine Acrosomal Vesicle Protein 1 (ACRV1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Equine Acrosomal Vesicle Protein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACRV1 level test of animal Equine/Horse with Fertilization.
Tag	His
Products description	Recombinant Equine ACRV1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-ACRV1-Ab01, GMP-EQU-ACRV1-Ab02
Product Name	Anti-Equine ACRV1 mouse monoclonal antibody (mAb)
Target/Biomarker	Equine Acrosomal Vesicle Protein 1 (ACRV1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Equine Acrosomal Vesicle Protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies in ACRV1 level test of animal Equine/Horse with Fertilization.
Tag	mFc
Products description	Anti-Equine ACRV1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-EQU-ACRV1-Ab03, GMP-EQU-ACRV1-Ab04
Product Name	Anti-Equine ACRV1 human monoclonal antibody (mAb)
Target/Biomarker	Equine Acrosomal Vesicle Protein 1 (ACRV1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Equine Acrosomal Vesicle Protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies in ACRV1 level test of animal Equine/Horse with Fertilization.
Tag	hFc
Products description	Anti-Equine ACRV1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACRV1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Equine ACRV1, also referred to as Acrosome Protein ACRV1, occupies a central position in the intricate choreography of equine reproduction. This protein is primarily housed within the acrosome, an organelle that graces the head of mature sperm, and its significance extends to one of life's most vital processes: fertilization. Structurally, ACRV1 is a glycoprotein that constitutes a significant portion of the acrosome's composition. The acrosome, a sac-like structure, contains enzymes and proteins crucial for sperm-egg interaction and penetration. ACRV1's role commences at the moment of sperm-egg contact, where it engages in sperm-egg binding and membrane fusion, initiating the complex process of fertilization. The acrosomal reaction, masterminded in part by ACRV1, unfolds as the sperm approaches the egg. It involves the release of acrosomal enzymes that digest the zona pellucida, a glycoprotein-rich layer surrounding the egg. ACRV1 contributes to the breakdown of the zona pellucida, facilitating the penetration of the egg's protective layers. Beyond its role in fertilization, ACRV1 is believed to be involved in the formation and maintenance of the acrosome itself. A well-formed and intact acrosome is vital for sperm function, and any disruptions in ACRV1 expression or function can impact the structural integrity of the acrosome.

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