Canine sFlt-1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-sFlt-1-Ag01	Recombinant Canine sFlt-1 protein	3090
GMP-CAN-sFlt-1-Ab01	Anti-Canine sFlt-1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-sFlt-1-Ab02	Anti-Canine sFlt-1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-sFlt-1-Ab03	Anti-Canine sFlt-1 human monoclonal antibody (mAb)	1953
GMP-CAN-sFlt-1-Ab04	Anti-Canine sFlt-1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-sFlt-1-Ag01
Product Name	Recombinant Canine sFlt-1 protein
Target/Biomarker	Canine soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine soluble vascular endothelial growth factor receptor-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer.
Tag	His
Products description	Recombinant Canine sFlt-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-sFlt-1-Ab01, GMP-CAN-sFlt-1-Ab02
Product Name	Anti-Canine sFlt-1 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine soluble vascular endothelial growth factor receptor-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies in sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer.
Tag	mFc
Products description	Anti-Canine sFlt-1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-sFlt-1-Ab03, GMP-CAN-sFlt-1-Ab04
Product Name	Anti-Canine sFlt-1 human monoclonal antibody (mAb)
Target/Biomarker	Canine soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine soluble vascular endothelial growth factor receptor-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies in sFlt-1 level test of animal Dog/Canine with ascular diseases and cancer.
Tag	hFc
Products description	Anti-Canine sFlt-1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-sFlt-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Soluble Fms-Like Tyrosine Kinase-1 (sFlt-1) in dogs (canines) is a pivotal biomarker with multifaceted roles in vascular health and angiogenesis regulation. It is a soluble receptor that functions by binding to and neutralizing vascular endothelial growth factor (VEGF) and placental growth factor (PlGF), thereby modulating their biological effects. In healthy adult dogs, sFlt-1 levels are typically tightly regulated, contributing to the maintenance of normal vascular function. Structurally, sFlt-1 is a truncated form of the transmembrane receptor, Fms-like tyrosine kinase-1 (Flt-1). Unlike the membrane-bound form, sFlt-1 lacks the transmembrane domain, making it soluble and capable of circulating in the bloodstream. This solubility allows sFlt-1 to act as a decoy receptor, sequestering VEGF and PlGF and preventing them from binding to their cellular receptors.

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