Canine hEGF antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-hEGF-Ag01	Recombinant Canine hEGF protein	3090
GMP-CAN-hEGF-Ab01	Anti-Canine hEGF mouse monoclonal antibody (mAb)	1953
GMP-CAN-hEGF-Ab02	Anti-Canine hEGF mouse monoclonal antibody (mAb)	1953
GMP-CAN-hEGF-Ab03	Anti-Canine hEGF human monoclonal antibody (mAb)	1953
GMP-CAN-hEGF-Ab04	Anti-Canine hEGF human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-CAN-hEGF-Ag01
Product Name	Recombinant Canine hEGF protein
Target/Biomarker	Canine Human Epidermal Growth Factor (hEGF)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Human Epidermal Growth Factor antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in hEGF level test of animal Dog/Canine with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	His
Products description	Recombinant Canine hEGF protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-hEGF-Ab01, GMP-CAN-hEGF-Ab02
Product Name	Anti-Canine hEGF mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Human Epidermal Growth Factor (hEGF)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Human Epidermal Growth Factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies in hEGF level test of animal Dog/Canine with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	mFc
Products description	Anti-Canine hEGF mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-hEGF-Ab03, GMP-CAN-hEGF-Ab04
Product Name	Anti-Canine hEGF human monoclonal antibody (mAb)
Target/Biomarker	Canine Human Epidermal Growth Factor (hEGF)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Human Epidermal Growth Factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies in hEGF level test of animal Dog/Canine with lung cancer, anal cancers, glioblastoma and epithelian tumors of the head and neck.
Tag	hFc
Products description	Anti-Canine hEGF human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-hEGF antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Human Epidermal Growth Factor (hEGF) is a protein with profound implications in cell biology and tissue repair. While its name suggests a human origin, EGF-like molecules and signaling pathways have also been identified in dogs (canines), albeit with structural variations. EGF is a member of the epidermal growth factor family, which encompasses various proteins involved in regulating cell growth, proliferation, and tissue regeneration. The primary receptor for EGF is the Epidermal Growth Factor Receptor (EGFR), which is present on the surface of numerous cell types. When EGF binds to EGFR, it triggers a series of intracellular events that ultimately stimulate cell division, tissue repair, and the maintenance of healthy epithelial tissues. In dogs, EGF-like molecules and their corresponding signaling pathways exhibit functional similarities to their human counterparts. While the precise structure of EGF in dogs may differ from that in humans, the fundamental principles of EGF-mediated cellular responses are conserved. This implies that EGF pathways play essential roles in canine physiology, contributing to tissue homeostasis, repair, and regeneration.

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