Canine cTnT antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-cTnT-Ag01	Recombinant Canine cTnT protein	3090
GMP-CAN-cTnT-Ab01	Anti-Canine cTnT mouse monoclonal antibody (mAb)	1953
GMP-CAN-cTnT-Ab02	Anti-Canine cTnT mouse monoclonal antibody (mAb)	1953
GMP-CAN-cTnT-Ab03	Anti-Canine cTnT human monoclonal antibody (mAb)	1953
GMP-CAN-cTnT-Ab04	Anti-Canine cTnT human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-cTnT-Ag01
Product Name	Recombinant Canine cTnT protein
Target/Biomarker	Canine cardiac troponin T (cTnT)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine cardiac troponin T antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnT level test of animal Dog/Canine with hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy..
Tag	His
Products description	Recombinant Canine cTnT protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-cTnT-Ab01, GMP-CAN-cTnT-Ab02
Product Name	Anti-Canine cTnT mouse monoclonal antibody (mAb)
Target/Biomarker	Canine cardiac troponin T (cTnT)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine cardiac troponin T antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnT antibodies in cTnT level test of animal Dog/Canine with hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy..
Tag	mFc
Products description	Anti-Canine cTnT mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnT antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-cTnT-Ab03, GMP-CAN-cTnT-Ab04
Product Name	Anti-Canine cTnT human monoclonal antibody (mAb)
Target/Biomarker	Canine cardiac troponin T (cTnT)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine cardiac troponin T antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnT antibodies in cTnT level test of animal Dog/Canine with hypertrophic cardiomyopathy, restrictive and dilated cardiomyopathy..
Tag	hFc
Products description	Anti-Canine cTnT human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnT antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cardiac Troponin T (cTnT) in dogs is a specialized protein that plays a critical role in the regulation of muscle contraction in the heart. It is a component of the troponin complex, a set of proteins that control the interaction between actin and myosin, facilitating cardiac muscle contraction. Importantly, cTnT is unique to cardiac muscle cells, making it a highly specific biomarker for heart-related issues. When cardiac muscle cells in the dog's heart become damaged or stressed, cTnT is released into the bloodstream. This release occurs due to the disruption of the sarcomere structure in cardiac muscle, which allows cTnT to escape from the cells. As a result, cTnT levels in the blood become elevated, serving as a clear indicator of cardiac muscle injury. Veterinarians utilize cTnT measurements to diagnose cardiac conditions in dogs accurately. These measurements help confirm the presence of cardiac muscle damage, determine its extent, and guide treatment strategies. Monitoring cTnT levels over time enables veterinarians to assess the progress of treatment and the overall cardiac health of canine patients.

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