Canine VLP-1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-VLP-1-Ag01	Recombinant Canine VLP-1 protein	3090
GMP-CAN-VLP-1-Ab01	Anti-Canine VLP-1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-VLP-1-Ab02	Anti-Canine VLP-1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-VLP-1-Ab03	Anti-Canine VLP-1 human monoclonal antibody (mAb)	1953
GMP-CAN-VLP-1-Ab04	Anti-Canine VLP-1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-VLP-1-Ag01
Product Name	Recombinant Canine VLP-1 protein
Target/Biomarker	Canine Visinin-like protein 1 (VLP-1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Visinin-like protein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in VLP-1 level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Canine VLP-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-VLP-1-Ab01, GMP-CAN-VLP-1-Ab02
Product Name	Anti-Canine VLP-1 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Visinin-like protein 1 (VLP-1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Visinin-like protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-VLP-1 antibodies in VLP-1 level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Canine VLP-1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-VLP-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-VLP-1-Ab03, GMP-CAN-VLP-1-Ab04
Product Name	Anti-Canine VLP-1 human monoclonal antibody (mAb)
Target/Biomarker	Canine Visinin-like protein 1 (VLP-1)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Visinin-like protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-VLP-1 antibodies in VLP-1 level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Canine VLP-1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-VLP-1 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine Vaccinia-Like Particles-1 (VLP-1) stands as a remarkable biomarker, emblematic of the intricate tapestry of the canine immune system. At its core, VLP-1 is a unique molecular structure, reminiscent of viral particles, yet devoid of the genetic material necessary for viral replication. It primarily comprises protein subunits, enveloping canine DNA fragments within its core. VLP-1's emergence on the immunological stage is characterized by its role as an immune system sentinel. When dogs encounter pathogens or undergo vaccination, their immune response swings into action. As part of this orchestrated defense, VLP-1 is synthesized and released by immune cells. Its presence acts as a clarion call, signaling the activation of the immune system, particularly in response to viral antigens. It is crucial to emphasize that VLP-1 is not a pathogenic entity; instead, it serves as an amplification mechanism for the canine immune response. Its virus-like structure triggers a robust immunological reaction, priming the immune defenses to recognize and combat actual viral invaders with enhanced precision and potency. This process underpins the foundation of effective immune responses in dogs.

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